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Effects of Sleep Duration on Eating and Activity Behaviors

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ClinicalTrials.gov Identifier: NCT01030107
Recruitment Status : Completed
First Posted : December 11, 2009
Last Update Posted : October 5, 2012
Sponsor:
Collaborator:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The purpose of the proposed study is to determine whether the amount children sleep is associated with changes in hormones, hunger, motivation to eat, and food intake. Fifty children 8-11 years old who sleep 9-10 hours per night will be enrolled for a 3-week study. For 1 week each, children will be asked to sleep their typical amount, increase their sleep by 1-½ hours, and decrease their sleep by 1-½ hours. Half of the children will be asked to increase their sleep first and half to decrease their sleep first. During each week, the following will be gathered: sleep duration (measured by actigraphy, which is a small device that measures sleep), levels of hormones measured through blood draws, self-reported hunger and appetite, food intake (measured by 3 days of 24-hour recall), how motivated children are to eat (measured using a computer activity), and child height and weight. We believe that when children sleep less they will show changes in hormones associated with hunger and appetite, report being hungrier, be more motivated to eat, and eat more food.

Condition or disease Intervention/treatment
Sleep Obesity Behavioral: Increase Sleep Behavioral: Decrease Sleep

Study Design

Study Type : Observational
Actual Enrollment : 37 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Sleep Duration and Pediatric Overweight: the Role of Eating Behaviors
Study Start Date : February 2009
Primary Completion Date : January 2012
Study Completion Date : January 2012
Groups and Cohorts

Group/Cohort Intervention/treatment
Children with Insufficient Sleep
Children who sleep approximately 9-10 hours/night
Behavioral: Increase Sleep
Children are asked to increase their sleep by approximately 1 1/2 hours/night for 1 week.
Behavioral: Decrease Sleep
Children are asked to decrease their sleep by approximately 1 1/2 hours/night.


Outcome Measures

Primary Outcome Measures :
  1. absolute reinforcing value of food as compared to sedentary activities [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ]

Secondary Outcome Measures :
  1. plasma levels of leptin and ghrelin [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ]
  2. caloric intake [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ]
  3. levels of physical activity [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ]
  4. subjective ratings of hunger and appetite [ Time Frame: after 1 week of typical sleep duration, after 1 week of decreased sleep duration, after 1 week of increased sleep duration ]

Biospecimen Retention:   Samples Without DNA
2 ml of whole blood drawn at each of 3 assessments

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   8 Years to 11 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Children ages 8-11 years old recruited from Southeastern New England.
Criteria

Inclusion Criteria:

  • Age 8-11 years old
  • BMI for age and gender > 5th percentile (but no greater than 100% overweight)
  • Sleep approximately 9-10 hours nightly
  • Attend elementary school
  • Like at least 1 food and 1 activity used in the reinforcement paradigm
  • Able to understand and complete the reinforcement paradigm

Exclusion Criteria:

  • Existence of a diagnosable sleep disorder
  • Medical or psychiatric condition that could influence sleep or weight
  • Onset of menarche
  • Inability to complete study materials, including diagnosed disabilities
  • Dietary restrictions/allergies to foods used in the study that preclude them from study participation
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01030107


Locations
United States, Rhode Island
Weight Control and Diabetes Research Center
Providence, Rhode Island, United States, 02903
Sponsors and Collaborators
The Miriam Hospital
American Diabetes Association
Investigators
Principal Investigator: Chantelle N Hart, PhD The Miriam Hospital/Alpert Medical School of Brown University
More Information

Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: The Miriam Hospital
ClinicalTrials.gov Identifier: NCT01030107     History of Changes
Other Study ID Numbers: 1-08-JF-17
First Posted: December 11, 2009    Key Record Dates
Last Update Posted: October 5, 2012
Last Verified: April 2011

Keywords provided by The Miriam Hospital:
sleep
obesity
children
eating behaviors
activity
leptin
ghrelin