The Impact of Hospitalization on Ambulatory Blood Pressure and Intraocular Pressure

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01029860
Recruitment Status : Completed
First Posted : December 10, 2009
Last Update Posted : December 17, 2009
Information provided by:
Aristotle University Of Thessaloniki

Brief Summary:
The purpose of this study is to assess the effect of hospital admission on 24-hour ambulatory blood pressure (ABP) in hypertensive subjects.Treated or untreated hypertensive adults with open angle glaucoma underwent in-hospital and outpatient 24-hour ABP monitoring, in random order 4 weeks apart.

Condition or disease
Blood Pressure

Study Type : Observational
Actual Enrollment : 40 participants
Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: A Study Investigating the Impact of Hospitalization on Ambulatory Blood Pressure and Intraocular Pressure in Subjects With Mild to Moderate Arterial Hypertension and Untreated Ocular Hypertension
Study Start Date : March 2007
Actual Primary Completion Date : January 2009
Actual Study Completion Date : March 2009

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Ages Eligible for Study:   30 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Subjects with untreated ocular hypertension and stage 1 arterial hypertension with or without treatment with anti-hypertensive agents.

Inclusion Criteria:

  • age >30 years old.
  • subject has signed an informed consent.
  • patient has untreated ocular hypertension (IOP at 10:00 between 22-34 mm Hg)
  • patient has stage 1 arterial hypertension with or without therapy

Exclusion Criteria:

  • secondary hypertension.
  • stage 2 or 3 hypertension, history of renal disease.
  • sleep apnea.
  • diabetes mellitus
  • acute or chronic inflammation.
  • myocardial infarction or unstable angina within the past 6 months.
  • heart failure NYHA class III-IV.
  • active liver disease.
  • pregnancy.
  • history of drug or alcohol abuse, or any other condition with poor prognosis.
  • treatment with non-steroid anti-inflammatory agents, corticosteroids, beta-blockers, or any other regimen that could affect BP levels.
  • smoking

Responsible Party: Anastasios Lasaridis, 1st Department of Internal Medicine, Aristotle University, Thessaloniki Identifier: NCT01029860     History of Changes
Other Study ID Numbers: A3244
First Posted: December 10, 2009    Key Record Dates
Last Update Posted: December 17, 2009
Last Verified: March 2007

Keywords provided by Aristotle University Of Thessaloniki:
Ambulatory measurement