Pharmacogenetics of Propofol and Depth of Anesthesia
|ClinicalTrials.gov Identifier: NCT01029379|
Recruitment Status : Completed
First Posted : December 10, 2009
Last Update Posted : March 4, 2013
Propofol, (2,6-diisopropylphenol) is a short-acting anesthetic drug used for induction and maintenance of anesthesia.
The aim of this study is to evaluate plasma concentrations of propofol in relation to depth of anesthesia, measured by continuous EEG and to correlate plasma concentrations with genetic analyses of liver enzymes responsible for drug elimination.
Our hypothesis is that there is an individual requirement of Propofol plasma concentration depending on genetic differences in drug elimination.
200 patients, ASA classification 1, planned for elective surgery of a duration of at least 30 minutes will be included in this study.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||100 participants|
|Official Title:||The Effect of Pharamocogenetices on Anesthesia Induction With Propofol|
|Study Start Date :||January 2010|
|Primary Completion Date :||February 2013|
|Study Completion Date :||February 2013|
|200 patients,ASA 1|
- EEG pattern in correlation to clinical anesthesia [ Time Frame: 20120101 ]EEG pattern in correlation to clinical anesthesia
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01029379
|Department of Anesthesia and Intensive Care|