Comparison of Laparoscopic Nissen Versus Thal Fundoplication in Children
Laparoscopic fundoplication is increasingly performed in paediatric surgery. Many types of fundoplication are performed, each has advantages and disadvantages. The Nissen operation is the most frequently performed procedure in the U.K., however it can be associated with post-operative dysphagia. The relative benefits between Nissen and other fundoplication techniques in children are still uncertain.
The aim of our study was to compare the long-term outcomes following laparoscopic Nissen fundoplication with laparoscopic Thal fundoplication in children.
|Gastroesophageal Reflux Disease||Procedure: laparoscopic Nissen/laparoscopic Thal|
|Study Design:||Primary Purpose: Treatment|
|Official Title:||Long-term Outcome of Laparoscopic Nissen Fundoplication Compared With Laparoscopic Thal Fundoplication in Children|
- Recurrence of symptoms sufficiently severe to justify the need for additional revisional surgery (i.e. failure of the original surgery)
- Early death following surgery directly related to the fundoplication technique
- The resumption of symptoms bad enough to necessitate the re-introduction of anti-reflux medication (but not sufficiently bad to require revisional surgery) i.e. "intention to treat"
- Post-operative complications (e.g. post-operative dysphagia)
|Study Start Date:||July 1998|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01027975
|Department of Paediatric Surgery, John Radcliffe Hospital NHS Trust|
|Oxford (Headington), Oxford, United Kingdom, OX3 9DU|
|Study Director:||Hugh W Grant, MD||John Radcliffe Hospital, Department of Paediatric Surgery, Oxford,United Kingdom|
|Principal Investigator:||Rainer Kubiak, MD||John Radcliffe Hospital, Department of Paediatric Surgery, Oxford, United Kingdom|