Assessment of Ability Related to Vision (AARV)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01027312
Recruitment Status : Completed
First Posted : December 7, 2009
Last Update Posted : November 22, 2016
Information provided by (Responsible Party):
George L. Spaeth MD, Wills Eye

Brief Summary:
To determine the clinical usefulness of a refined third-generation instrument - The Assessment of Ability Related to Vision (AARV) in establishing the amount of disability, charting the detrimental effects of progressive disease and establishing the beneficial effects of treatment

Condition or disease

Detailed Description:

This research study is designed to test the usefulness and repeatability of testing how much disability is caused by vision loss due to glaucoma. We are recruiting 100 patients with glaucoma and 20 healthy (have no eye disease) individuals to be enrolled in this study. The healthy study participants will be enrolled in order to describe how a healthy individual will perform on the test designed to assess one's performance when completing ten activities of daily living.

Clinical testing will be conducted by binocular and monocular visual fields, contrast sensitivity and visual acuity. The NEI-VFQ 15 Quality of Life Questionnaire will be used to measure patients perception of how well they are doing.

Study Type : Observational
Actual Enrollment : 121 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Reproducibility and Clinical Usefulness of AARV (Assessment of Ability Related to Vision)
Study Start Date : February 2008
Actual Primary Completion Date : August 2010
Actual Study Completion Date : August 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Glaucoma

Glaucoma Patients
Glaucoma patients covering the entire range of visual field loss from none to advanced.
Control Group
Aged matched people with no eye diseases.

Primary Outcome Measures :
  1. the reproducibility of AARV, and its relationship to standard clinical tests [ Time Frame: Day 1, 1 week, 6 months, 1 year ]

Secondary Outcome Measures :
  1. A better estimate of the reproducibility of standard clinical tests. [ Time Frame: Day 1, 1 week, 6 months, 1 year ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
One hundred patients with bilateral unstable glaucoma and twenty patients who appear to be normal will be enrolled.

Inclusion Criteria:

  • All patients 18 yrs of age and older
  • must understand and respond to spoken English and be fully literate.

Exclusion Criteria:

  • Patients with significant neurological problems (like Parkinson's disease), motor problems (like arthritis) or other significant illnesses that may prevent them from completing the testing involved in the study (like advanced heart failure).
  • Patients who have received training related to low vision.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01027312

Sponsors and Collaborators
Wills Eye
Principal Investigator: George L Spaeth, MD Wills Eye Institute

Publications of Results:
Responsible Party: George L. Spaeth MD, Principal Investigator, Wills Eye Identifier: NCT01027312     History of Changes
Other Study ID Numbers: IRB#07-842
First Posted: December 7, 2009    Key Record Dates
Last Update Posted: November 22, 2016
Last Verified: November 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Yes
Plan Description: A manuscript has been written and published

Keywords provided by George L. Spaeth MD, Wills Eye:
quality of life
daily living activities
visual fields
contrast sensitivity

Additional relevant MeSH terms:
Ocular Hypertension
Eye Diseases