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Respiratory Muscle Endurance Training in Obese Patients

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ClinicalTrials.gov Identifier: NCT01026155
Recruitment Status : Completed
First Posted : December 4, 2009
Last Update Posted : December 4, 2009
Sponsor:
Information provided by:
Fondation Edith Seltzer

Brief Summary:
Obese patients are known to have increased work of breathing inducing dyspnea, exercise intolerance and impaired quality of life. Respiratory muscle training is known to increase respiratory muscle capacity, reduce dyspnoea and improve exercise performance in healthy subjects and respiratory patients. The investigators hypothesized that Respiratory muscle training would reduce dyspnoea, increase exercise tolerance and quality of life in obese patients.

Condition or disease Intervention/treatment Phase
Obesity Other: Respiratory muscle training Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: Respiratory Muscle Endurance Training in Obese Patients

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: Respiratory muscle traininig
Low caloric diet and physical activities + Respiratory muscle endurance training by means of isocapnic voluntary hyperpnoea
Other: Respiratory muscle training
Respiratory muscle endurance training by means of isocapnic voluntary hyperpnoea
Active Comparator: Control
Low caloric diet and physical activities
Other: Respiratory muscle training
Respiratory muscle endurance training by means of isocapnic voluntary hyperpnoea



Primary Outcome Measures :
  1. Dyspnea at rest and during exercise

Secondary Outcome Measures :
  1. Exercise performance (6-min walking distance) Quality of life (SF36 questionnaire)


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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Obese patients (BMI > 30 kg/m2), without respiratory pathology (VEMS > 80% predicted, VEMS/CV > 80%)
  • men or women
  • age between 18 and 60 years old

Exclusion Criteria:

  • Respiratory, cardiovascular, musculoskeletal diseases
  • Alcoholism

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01026155


Locations
France
Centre Bois de l'Ours
Briançon, France, 05107
Sponsors and Collaborators
Fondation Edith Seltzer
Investigators
Principal Investigator: Bernard Wuyam, MD PhD University Hospital, Grenoble

ClinicalTrials.gov Identifier: NCT01026155     History of Changes
Other Study ID Numbers: Respob
First Posted: December 4, 2009    Key Record Dates
Last Update Posted: December 4, 2009
Last Verified: December 2009

Keywords provided by Fondation Edith Seltzer:
Obese patients (BMI > 30 kg / m²)