We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Effects of Inulin on Satiety and Food Intake (Inulin)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01025375
First Posted: December 3, 2009
Last Update Posted: August 30, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Maastricht University Medical Center
  Purpose
To assess the effect of inulin on appetite profile ratings, food intake and satiety hormones.

Condition Intervention
Obesity Dietary Supplement: inulin Dietary Supplement: placebo

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Investigator)
Official Title: Effects of Inulin on Satiety and Food Intake

Resource links provided by NLM:


Further study details as provided by Maastricht University Medical Center:

Primary Outcome Measures:
  • food intake [ Time Frame: on testday 0 and 13 ]

Secondary Outcome Measures:
  • appetite profile ratings [ Time Frame: on test day 0, 8 and 13 (at 16 time points) ]
  • satiety hormones (GLP-1 and PYY) [ Time Frame: on test day 0 and 13 (at 9 time points ]

Enrollment: 30
Study Start Date: January 2009
Study Completion Date: February 2010
Primary Completion Date: February 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Dietary Supplement: inulin
    10gram/day inulin for 13-day treatment
    Other Name: oligofructose
    Dietary Supplement: inulin
    16gram/day inulin for 13-day treatment
    Other Name: oligofructose
    Dietary Supplement: placebo
    16gram/day maltodextrin (placebo) for 13-day treatment
    Other Name: maltodextrin
Detailed Description:
Based upon a slower digestion and the fermentation in the intestinal tract, food containing soluble dietary fibres, such as inulin, is hypothesized to be more satiating, and to limit energy intake, in humans. Does supplementation of inulin (at 2 dosages) versus placebo over 13 consecutive days in normal to overweight men and women, lead to an increase in satiety, a reduction in food intake and stronger postprandial increases in GLP-1 and PYY?
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • age between 18 and 60 years
  • BMI between 23 and 28 kg/m2
  • dietary unrestraint (TFEQ: F1<9)

Exclusion Criteria:

  • age under 18 and above 60 years
  • BMI under 23 and above 28 kg/m2
  • dietary restraint (TFEQ: F1>9)
  • use of medication
  • pregnant or breastfeeding
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01025375


Locations
Netherlands
Maastricht University
Maastricht, Limburg, Netherlands, 6229ER
Sponsors and Collaborators
Maastricht University Medical Center
Investigators
Principal Investigator: Klaas R Westerterp, Prof NUTRIM
  More Information

Responsible Party: Maastricht University Medical Center
ClinicalTrials.gov Identifier: NCT01025375     History of Changes
Other Study ID Numbers: HumBio_Westerterp08_2
First Submitted: December 2, 2009
First Posted: December 3, 2009
Last Update Posted: August 30, 2012
Last Verified: August 2012

Keywords provided by Maastricht University Medical Center:
overweight