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Apathy in Parkinson Disease: Clinical, Physiopathological and Pharmacological Study

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified November 2009 by University Hospital, Grenoble.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01020682
First Posted: November 25, 2009
Last Update Posted: November 25, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Institut National de la Santé Et de la Recherche Médicale, France
Information provided by:
University Hospital, Grenoble
  Purpose
Apathy has been reported to occur after subthalamic nucleus stimulation (STN-DBS), a treatment of motor complications in advanced Parkinson's disease (PD). It is not known whether postoperative apathy is related to dopamine withdrawal or a side effect of STN DBS. The researchers investigated potential predictors of apathy, and the effect of dopamine agonist treatment.

Condition
Apathy in Parkinson Disease

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Apathy in Parkinson Disease: Clinical, Physiopathological and Pharmacological Study

Resource links provided by NLM:


Further study details as provided by University Hospital, Grenoble:

Estimated Enrollment: 120
Study Start Date: January 2005
Estimated Study Completion Date: June 2011
Primary Completion Date: February 2006 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Parkinson's disease
Criteria

Inclusion Criteria:

  • Parkinson disease

Exclusion Criteria:

  • Mattis scale < 130
  • Beck scale > 20
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01020682


Contacts
Contact: Krack Paul, MD 0476765791 paul.krack@ujf-grenoble.fr

Locations
France
Hopital neurologique Recruiting
Lyon, France, 69000
Contact: Broussolle , MD         
Sponsors and Collaborators
University Hospital, Grenoble
Institut National de la Santé Et de la Recherche Médicale, France
  More Information

Responsible Party: Délégation à la recherche clinique, CHU de grenoble
ClinicalTrials.gov Identifier: NCT01020682     History of Changes
Other Study ID Numbers: APATHIE
First Submitted: November 24, 2009
First Posted: November 25, 2009
Last Update Posted: November 25, 2009
Last Verified: November 2009

Keywords provided by University Hospital, Grenoble:
apathy
parkinson
agonist dopaminergic

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases