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Controlled Propofol Administration

This study has been completed.
Information provided by:
McGill University Health Center Identifier:
First received: November 23, 2009
Last updated: NA
Last verified: November 2009
History: No changes posted
The purpose of this study is to compare the administration of the standard anesthetic agent (propofol) using this automatic system with the manual administration of propofol by the anesthesiologist.

Condition Intervention Phase
HYPNOSIS Drug: propofol Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Comparison of Closed-oop of Propofol Versus Manual Control Using Bispectral Index (BIS)

Resource links provided by NLM:

Further study details as provided by McGill University Health Center:

Primary Outcome Measures:
  • Comparison of control administration of propofol with manual administration. [ Time Frame: 1 year ]

Secondary Outcome Measures:
  • Emergence from anesthesia [ Time Frame: 1 year ]

Estimated Enrollment: 40
Study Start Date: August 2007
Primary Completion Date: May 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: control propofol administration Drug: propofol
propofol administration


Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • patients aged 18 to 90 years
  • surgery lasting more than 30 min

Exclusion Criteria:

  • inability to provide informed consent
  • allergies to study drug
  Contacts and Locations
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Please refer to this study by its identifier: NCT01019746

Canada, Quebec
MUHC - Montreal General Hospital
Montreal, Quebec, Canada, H3G 1A4
Sponsors and Collaborators
McGill University Health Center
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: performance of a novel closed-loop propofol system, MUHC - Montreal General Hospitalization Identifier: NCT01019746     History of Changes
Other Study ID Numbers: GEN-07-002
Study First Received: November 23, 2009
Last Updated: November 23, 2009

Keywords provided by McGill University Health Center:
Hypnosis with propofol

Additional relevant MeSH terms:
Hypnotics and Sedatives
Central Nervous System Depressants
Physiological Effects of Drugs
Anesthetics, Intravenous
Anesthetics, General
Anesthetics processed this record on September 21, 2017