Preemptive Low-dose Epidural Ketamine for Preventing Chronic Post-thoracotomy Pain
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ClinicalTrials.gov Identifier: NCT01017393 |
Recruitment Status
:
Completed
First Posted
: November 20, 2009
Last Update Posted
: November 20, 2009
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Chronic Post-thoracotomy Pain | Drug: Ketamine Drug: ketamine free | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 209 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Triple (Participant, Care Provider, Investigator) |
Primary Purpose: | Prevention |
Study Start Date : | April 2004 |
Actual Primary Completion Date : | June 2005 |
Actual Study Completion Date : | June 2005 |

Arm | Intervention/treatment |
---|---|
Experimental: ketamine
epidural ketamine added to the patient controlled epidural analgesia regimen
|
Drug: Ketamine |
Active Comparator: ketamine free
epidural ketamine NOT added to the patient controlled epidural analgesia regimen
|
Drug: ketamine free |
- Incidence of pain 3 months after surgery [ Time Frame: 3 months after surgery ]

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Ages Eligible for Study: | 19 Years to 81 Years (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Patients undergoing surgery with a thoracotomy incision
Exclusion Criteria:
- history of previous thoracic surgery, chronic pain, psychiatric disease, cardiac or vascular disease, neurologic deficits, or contraindications to epidural catheterization such as coagulopathy, or localized or systemic infection

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01017393
Korea, Republic of | |
Seoul National University Hospital | |
Seoul, Korea, Republic of, 110-744 |
ClinicalTrials.gov Identifier: | NCT01017393 History of Changes |
Other Study ID Numbers: |
JHBahk_epidural ketamine PTPS |
First Posted: | November 20, 2009 Key Record Dates |
Last Update Posted: | November 20, 2009 |
Last Verified: | November 2009 |
Keywords provided by Seoul National University Hospital:
preemptive epidural ketamine prevention of chronic post-thoracotomy pain |
Additional relevant MeSH terms:
Ketamine Analgesics Sensory System Agents Peripheral Nervous System Agents Physiological Effects of Drugs Anesthetics, Dissociative Anesthetics, Intravenous |
Anesthetics, General Anesthetics Central Nervous System Depressants Excitatory Amino Acid Antagonists Excitatory Amino Acid Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action |