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Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae

This study has been terminated.
(not enough patients enrolled)
Information provided by (Responsible Party):
Gerhard Rogler, University of Zurich Identifier:
First received: November 11, 2009
Last updated: December 3, 2014
Last verified: December 2014
The investigators will study whether local instillation of Doxycycline and Acetylcystein results in fistula closure in CD patients.

Condition Intervention
Crohn's Disease
Procedure: Colonoscopy

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: FIST-MC-09 Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae

Resource links provided by NLM:

Further study details as provided by Gerhard Rogler, University of Zurich:

Primary Outcome Measures:
  • Fistula closure [ Time Frame: 01.08.2009 - 31.07.2012 ]

Estimated Enrollment: 20
Study Start Date: November 2009
Study Completion Date: July 2012
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Colonoscopy
    During the colonoscopy, we instill Acetylcystein and Doxycyline into the fistula.

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion criteria:

  • fistulizing CD
  • CD < 6 months
  • at least one insufficient fistula closure try

Exclusion criteria:

  • CDAI > 200
  • Abscesses
  • CRP > 100
  Contacts and Locations
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Please refer to this study by its identifier: NCT01012726

Zurich, Switzerland
Sponsors and Collaborators
Gerhard Rogler
Study Director: 01 Studienregister MasterAdmins UniversitaetsSpital Zuerich
  More Information

Responsible Party: Gerhard Rogler, Prof. Dr. Dr. Gerhard Rogler, University of Zurich Identifier: NCT01012726     History of Changes
Other Study ID Numbers: FIST-MC-09
Study First Received: November 11, 2009
Last Updated: December 3, 2014

Additional relevant MeSH terms:
Crohn Disease
Inflammatory Bowel Diseases
Gastrointestinal Diseases
Digestive System Diseases
Intestinal Diseases
Pathological Conditions, Anatomical
Anti-Bacterial Agents
Anti-Infective Agents
Antiprotozoal Agents
Antiparasitic Agents processed this record on May 25, 2017