Red Cell Mass and Plasma Volume Measurements in Elderly Men and Women With Anemia
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On the basis that the clinical consequences of seemingly trivial levels of anemia are surprisingly severe, this study investigates if hemoglobin concentration accurately represents the underlying red cell mass in elderly patients with unresolved anemia.
Condition or disease
For the study, the routine clinical measurement of hemoglobin will be compared to true red cell mass and plasma volume in elderly patients with anemia.
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Ages Eligible for Study:
65 Years and older (Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Outpatient elderly men and women (aged 65 years or older) with anemia, also enrolled in the "Anemia in the Elderly" NCT00640172 study.
65 and older
Anemia (hemoglobin < 13 g/dL in men or < 12 g/dL in women)
Outpatient at either the Stanford Health Care (SHC) Medical Center or VA Palo Alto Health Care System
Body mass index (BMI):
< 18.5 kg/m2
> 35 kg/m2
Contraindication to RBC mass/plasma volume testing
On any experimental pharmacologic agent in the prior 2 months