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Different Metabolic Effects of Statins

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ClinicalTrials.gov Identifier: NCT01011127
Recruitment Status : Completed
First Posted : November 11, 2009
Last Update Posted : October 5, 2010
Sponsor:
Information provided by:
Gachon University Gil Medical Center

Brief Summary:
The investigators hypothesize that pravastatin and rosuvastatin may have different metabolic effects in hypercholesterolemic patients.

Condition or disease Intervention/treatment
Hypercholesterolemia Drug: pravastatin, rosuvastatin

Study Type : Observational
Observational Model: Case Control
Time Perspective: Prospective
Study Start Date : December 2009
Actual Primary Completion Date : July 2010
Actual Study Completion Date : August 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort Intervention/treatment
pravastatin Drug: pravastatin, rosuvastatin
rosuvastatin Drug: pravastatin, rosuvastatin




Information from the National Library of Medicine

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Ages Eligible for Study:   25 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Sampling Method:   Probability Sample
Study Population
Hypercholesterolemia
Criteria

Inclusion Criteria:

  • Low-density lipoprotein cholesterol levels>130

Exclusion Criteria:

  • Overt liver disease Chronic renal failure Hypothyroidism Myopathy Uncontrolled diabetes Severe hypertension

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01011127


Locations
Korea, Republic of
Gil Medical Center
Incheon, Korea, Republic of, 405-760
Sponsors and Collaborators
Gachon University Gil Medical Center

Publications:
ClinicalTrials.gov Identifier: NCT01011127     History of Changes
Other Study ID Numbers: GMC-200914
First Posted: November 11, 2009    Key Record Dates
Last Update Posted: October 5, 2010
Last Verified: October 2010

Keywords provided by Gachon University Gil Medical Center:
Statins
Insulin resistance

Additional relevant MeSH terms:
Hypercholesterolemia
Hyperlipidemias
Dyslipidemias
Lipid Metabolism Disorders
Metabolic Diseases
Rosuvastatin Calcium
Pravastatin
Anticholesteremic Agents
Hypolipidemic Agents
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Lipid Regulating Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Enzyme Inhibitors