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Different Metabolic Effects of Statins

This study has been completed.
Information provided by:
Gachon University Gil Medical Center Identifier:
First received: November 10, 2009
Last updated: October 4, 2010
Last verified: October 2010
The investigators hypothesize that pravastatin and rosuvastatin may have different metabolic effects in hypercholesterolemic patients.

Condition Intervention
Hypercholesterolemia Drug: pravastatin, rosuvastatin

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Gachon University Gil Medical Center:

Study Start Date: December 2009
Study Completion Date: August 2010
Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
pravastatin Drug: pravastatin, rosuvastatin
rosuvastatin Drug: pravastatin, rosuvastatin


Ages Eligible for Study:   25 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Sampling Method:   Probability Sample
Study Population

Inclusion Criteria:

  • Low-density lipoprotein cholesterol levels>130

Exclusion Criteria:

  • Overt liver disease Chronic renal failure Hypothyroidism Myopathy Uncontrolled diabetes Severe hypertension
  Contacts and Locations
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Please refer to this study by its identifier: NCT01011127

Korea, Republic of
Gil Medical Center
Incheon, Korea, Republic of, 405-760
Sponsors and Collaborators
Gachon University Gil Medical Center
  More Information

Publications: Identifier: NCT01011127     History of Changes
Other Study ID Numbers: GMC-200914
Study First Received: November 10, 2009
Last Updated: October 4, 2010

Keywords provided by Gachon University Gil Medical Center:
Insulin resistance

Additional relevant MeSH terms:
Lipid Metabolism Disorders
Metabolic Diseases
Rosuvastatin Calcium
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Anticholesteremic Agents
Hypolipidemic Agents
Molecular Mechanisms of Pharmacological Action
Enzyme Inhibitors
Lipid Regulating Agents processed this record on August 18, 2017