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Different Metabolic Effects of Statins

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01011127
Recruitment Status : Completed
First Posted : November 11, 2009
Last Update Posted : October 5, 2010
Information provided by:
Gachon University Gil Medical Center

Brief Summary:
The investigators hypothesize that pravastatin and rosuvastatin may have different metabolic effects in hypercholesterolemic patients.

Condition or disease Intervention/treatment
Hypercholesterolemia Drug: pravastatin, rosuvastatin

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Study Type : Observational
Observational Model: Case Control
Time Perspective: Prospective
Study Start Date : December 2009
Actual Primary Completion Date : July 2010
Actual Study Completion Date : August 2010

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
pravastatin Drug: pravastatin, rosuvastatin
rosuvastatin Drug: pravastatin, rosuvastatin

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   25 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Probability Sample
Study Population

Inclusion Criteria:

  • Low-density lipoprotein cholesterol levels>130

Exclusion Criteria:

  • Overt liver disease Chronic renal failure Hypothyroidism Myopathy Uncontrolled diabetes Severe hypertension

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01011127

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Korea, Republic of
Gil Medical Center
Incheon, Korea, Republic of, 405-760
Sponsors and Collaborators
Gachon University Gil Medical Center

Layout table for additonal information Identifier: NCT01011127    
Other Study ID Numbers: GMC-200914
First Posted: November 11, 2009    Key Record Dates
Last Update Posted: October 5, 2010
Last Verified: October 2010
Keywords provided by Gachon University Gil Medical Center:
Insulin resistance
Additional relevant MeSH terms:
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Lipid Metabolism Disorders
Metabolic Diseases
Rosuvastatin Calcium
Anticholesteremic Agents
Hypolipidemic Agents
Molecular Mechanisms of Pharmacological Action
Lipid Regulating Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Enzyme Inhibitors