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Can Airflow Limitation in Chronic Obstructive Pulmonary Disease (COPD) be Reversible by Drugs?

This study has been completed.
Information provided by:
Baqiyatallah Medical Sciences University Identifier:
First received: November 6, 2009
Last updated: NA
Last verified: November 2009
History: No changes posted
Critical combination of various approved drugs in management for patients suffering with COPD.

Condition Intervention Phase
Chronic Obstructive Pulmonary Disease
Drug: Macrolid, Theophylline, Inhaler Corticosteroids
Phase 4

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Combination of Approved Drug in COPD

Resource links provided by NLM:

Further study details as provided by Baqiyatallah Medical Sciences University:

Primary Outcome Measures:
  • 15% increasing in forced expiratory volume in 1 second [ Time Frame: 6 months ]

Enrollment: 64
Study Start Date: February 2008
Study Completion Date: July 2009
Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Macrolid, Theophylline, Corticosteroids
Approved drug in this setting
Drug: Macrolid, Theophylline, Inhaler Corticosteroids
we have no permission to include them in detail because of privacy policy of mentioned journal for publication


Ages Eligible for Study:   22 Years to 86 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • current or past smoker COPD

Exclusion Criteria:

  • history of significant occupational or other environmental exposures or a connective tissue disease
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Please refer to this study by its identifier: NCT01010178

Iran, Islamic Republic of
Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University, Mollasadra St,
Tehran, Iran, Islamic Republic of, 19945-546
Sponsors and Collaborators
Baqiyatallah Medical Sciences University
  More Information

Responsible Party: Corresponding Author: Research Center of Chemical Injuries, Baqiyatallah Medical Sciences University Identifier: NCT01010178     History of Changes
Other Study ID Numbers: BMT-1388-2
Study First Received: November 6, 2009
Last Updated: November 6, 2009

Keywords provided by Baqiyatallah Medical Sciences University:
symptoms PFT

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases
Bronchodilator Agents
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anti-Asthmatic Agents
Respiratory System Agents
Phosphodiesterase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Vasodilator Agents
Purinergic P1 Receptor Antagonists
Purinergic Antagonists
Purinergic Agents
Neurotransmitter Agents processed this record on May 22, 2017