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The Dynamics of Human Atrial Fibrillation

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2013 by University of California, San Diego.
Recruitment status was:  Recruiting
National Heart, Lung, and Blood Institute (NHLBI)
Information provided by (Responsible Party):
Sanjiv Narayan, MD, PhD, University of California, San Diego Identifier:
First received: November 5, 2009
Last updated: December 10, 2013
Last verified: December 2013
The study is conducted in patients with atrial fibrillation undergoing clinically prescribed ablation. The study hypothesis is that ablation at specific sites that are identified to 'drive' the atrial fibrillation may improve the success of the ablation procedure.

Atrial Fibrillation
Atrial Tachyarrhythmia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Dynamics of Human Atrial Fibrillation

Resource links provided by NLM:

Further study details as provided by University of California, San Diego:

Primary Outcome Measures:
  • Survival Free of Atrial Fibrillation [ Time Frame: 6 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Termination of atrial fibrillation during ablation [ Time Frame: acute ] [ Designated as safety issue: No ]

Estimated Enrollment: 98
Study Start Date: June 2009
Estimated Study Completion Date: May 2014
Estimated Primary Completion Date: April 2014 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   21 Years to 80 Years   (Adult, Senior)
Genders Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Subjects will be men and women of all races aged 21 to 80 years undergoing clinically indicated ablation of Atrial Fibrillation.

Inclusion Criteria:

  • Subjects will be patients undergoing electrophysiology study and ablation for paroxysmal or persistent atrial fibrillation (AF) after having failed >or= 1 anti-arrhythmic drug.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01008722

United States, California
University of California, San Diego
La Jolla, California, United States, 92093
VA San Diego Medical Center
San Diego, California, United States, 92161
Sponsors and Collaborators
University of California, San Diego
National Heart, Lung, and Blood Institute (NHLBI)
Principal Investigator: Sanjiv M. Narayan, MD, PhD University of California, San Diego
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Sanjiv Narayan, MD, PhD, Professor of Medicine, University of California, San Diego Identifier: NCT01008722     History of Changes
Other Study ID Numbers: 684  R01HL083359 
Study First Received: November 5, 2009
Last Updated: December 10, 2013
Health Authority: United States: Federal Government

Keywords provided by University of California, San Diego:
Atrial Fibrillation

Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes processed this record on January 18, 2017