EPT 100: Geranium Oil for the Relief of Neuropathic Pain (Geranium Oil)

This study has been completed.
Information provided by (Responsible Party):
Frank Greenway, Pennington Biomedical Research Center
ClinicalTrials.gov Identifier:
First received: November 3, 2009
Last updated: December 17, 2015
Last verified: December 2015
The purpose of this study is to determine if Geranium oil will relieve a variety of neuropathic pain and some pain relief will last more than 48 hours.

Condition Intervention
Neuropathic Pain
Other: Geranium oil

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: EPT 100: Geranium Oil for the Relief of Neuropathic Pain

Further study details as provided by Pennington Biomedical Research Center:

Primary Outcome Measures:
  • Pain relief [ Time Frame: 3 times in 30 to 60 minutes post-application ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Response to therapy at 30 to 60 minutes, they will be asked to apply the oil to painful area daily [ Time Frame: Daily over 1 week ] [ Designated as safety issue: No ]

Enrollment: 166
Study Start Date: November 2008
Study Completion Date: October 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Geranium oil Other: Geranium oil
Daily topical application over neuropathic pain

Detailed Description:
EPT 100 study is designed to identify the percentage of people who experience neuropathic pain relief from topical geranium oil from Reunion Island, determine which neuropathic pain conditions respond best and define the time course of the pain relief.

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 18 years of age or oler
  • Neuralgia or neuropathy with daily pain
  • At least moderate intensity pain
  • Signed informed consent

Exclusion Criteria:

  • Pregnant or nursing
  • Known allergies to geranium oil or geranium oil fractions
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01007747

United States, Louisiana
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808
Sponsors and Collaborators
Pennington Biomedical Research Center
  More Information

Responsible Party: Frank Greenway, Clinical Medical Doctor, Pennington Biomedical Research Center
ClinicalTrials.gov Identifier: NCT01007747     History of Changes
Other Study ID Numbers: PBRC 21033 
Study First Received: November 3, 2009
Last Updated: December 17, 2015
Health Authority: United States: Institutional Review Board

Keywords provided by Pennington Biomedical Research Center:
Geranium oil

Additional relevant MeSH terms:
Nervous System Diseases
Neurologic Manifestations
Neuromuscular Diseases
Peripheral Nervous System Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on May 22, 2016