Multifunctional Magnetic Resonance (MR) for Radiotherapy Planning in Prostate Cancer
|ClinicalTrials.gov Identifier: NCT01006564|
Recruitment Status : Unknown
Verified November 2009 by Royal Marsden NHS Foundation Trust.
Recruitment status was: Recruiting
First Posted : November 3, 2009
Last Update Posted : November 3, 2009
|Condition or disease||Intervention/treatment|
|Prostate Cancer||Other: Imaging Investigations (not radiation) Other: Other|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||30 participants|
|Intervention Model:||Single Group Assignment|
|Official Title:||Multifunctional MR for Radiotherapy Planning in Prostate Cancer|
|Study Start Date :||March 2009|
|Estimated Primary Completion Date :||June 2011|
|Estimated Study Completion Date :||June 2011|
Other: Imaging Investigations (not radiation)
- Comparison of dose distributions produced by rival radiotherapy plans judged using radiobiological model predictions of Tumour Control Probability (TCP) and Normal Tissue Complication Probability (NTCP).
- Comparison of reproducibility of registration algorithms for mapping functional MR data acquired before hormone therapy to MR anatomical data acquired after hormone therapy and prior to radiotherapy.
- Comparison of reproducibility of registration of functional and MR data with computed tomography (CT) data using gold seed registration, assessing reproducibility and positioning issues.
- Comparison of image quality, registration reproducibility and gland distortion of internal and external imaging coils for MRI image acquisition and registration of the prostate.
- Comparison of dose distributions produced by rival radiotherapy plans judged using three standard dose-volume constraints for targets and normal tissues and careful examination of the 3D dose distribution.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01006564
|Contact: Dr Nandita deSouzaemail@example.com|
|Royal Marsden NHS Foundation Trust||Recruiting|
|Sutton, Surrey, United Kingdom, SM2 5PT|
|Principal Investigator:||Dr Nandita deSouza||CRUK Clinical Magnetic Resonance Research Group|