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The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.

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ClinicalTrials.gov Identifier: NCT01004588
Recruitment Status : Completed
First Posted : October 30, 2009
Last Update Posted : April 10, 2015
Sponsor:
Collaborator:
Top Institute Food and Nutrition
Information provided by (Responsible Party):
Maastricht University Medical Center

Brief Summary:
The main objective of this study is to examine the effects of resistance type exercise training combined with nutritional support on body composition and muscle characteristics in healthy elderly men and women. For a comprehensive insight into the potential underlying mechanisms of the intervention effects on whole body-, muscle- and myocellular level, a broad range of tests will be performed before, during, and after the intervention period.

Condition or disease Intervention/treatment Phase
Muscle Loss in Elderly Dietary Supplement: Protein drink Dietary Supplement: placebo drink Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: The Effects of Resistance Type Exercise Training and Protein Supplementation on Skeletal Muscle Mass, Strength, and Muscle Characteristics in Healthy Elderly Men and Women
Study Start Date : November 2009
Actual Primary Completion Date : November 2012
Actual Study Completion Date : November 2012

Arm Intervention/treatment
Experimental: Protein drink
protein drink
Dietary Supplement: Protein drink
total of 15 g protein/d in a protein drink consumed every morning after breakfast during 24 weeks

Placebo Comparator: Placebo drink
Placebo drink
Dietary Supplement: placebo drink
subjects consume a placebo drink every morning after breakfast over a period of 24 weeks.




Primary Outcome Measures :
  1. Change in muscle mass measured by DXA-scan and CT-scan [ Time Frame: 0, 12 and 24 weeks ]


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Ages Eligible for Study:   65 Years to 90 Years   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • over 65 years
  • healthy men and women

Exclusion Criteria:

  • cardiovascular disease
  • COPD
  • Parkinson
  • rheumatoid arthritis
  • musculoskeletal/orthopaedic disorders
  • cognitive impairment
  • subjects with metal implants

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01004588


Locations
Netherlands
Maastricht University
Maastricht, Netherlands
Sponsors and Collaborators
Maastricht University Medical Center
Top Institute Food and Nutrition
Investigators
Principal Investigator: Marika Leenders, MSc Maastricht University Medical Center

Responsible Party: Maastricht University Medical Center
ClinicalTrials.gov Identifier: NCT01004588     History of Changes
Other Study ID Numbers: MEC 09-3-056
First Posted: October 30, 2009    Key Record Dates
Last Update Posted: April 10, 2015
Last Verified: April 2015

Keywords provided by Maastricht University Medical Center:
elderly
sarcopenia
protein drink
resistance training