Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis (PACT)
This research investigates a new talking therapy aimed at helping people to come to terms with the experience of psychosis. The new therapy is called Acceptance and Commitment Therapy for psychosis (PACT). PACT aims to help people:
- Develop a sense of "mindfulness." Mindfulness allows you to be fully aware of your here-and-now experience, with an attitude of openness and curiosity. It is hoped that this will help reduce the impact of painful thoughts and feelings.
- Take effective action that is conscious and deliberate, rather than impulsive. It is hoped that this will allow people to be motivated, guided, and inspired by the things that they value in life.
It is hoped that PACT will help to reduce the level of distress that individuals diagnosed with psychosis have been experiencing and help them to stay well in the future.
Other: Acceptance and Commitment Therapy
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||A Pilot Randomised Controlled Trial of Acceptance and Commitment Therapy for Distress Following Psychosis|
- Measuring change in depression and anxiety [ Time Frame: Baseline and 3 month follow-up ] [ Designated as safety issue: No ]The Hospital Anxiety and Depression Scale
- Changes in believability, distress and frequency of positive symptoms [ Time Frame: Baseline and up to 9 months follow-up ] [ Designated as safety issue: No ]
- Measuring change in mindfulness skills and psychological flexibility [ Time Frame: Baseline and up to 9 month follow-up ] [ Designated as safety issue: No ]The Kentucky Inventory of Mindfulness Skills, The Acceptance and Action Questionnaire
|Study Start Date:||October 2009|
|Study Completion Date:||October 2010|
|Primary Completion Date:||October 2010 (Final data collection date for primary outcome measure)|
No Intervention: Treatment As Usual
Treatment as usual as determined by the clinical team responsible for the individual's care
Active Comparator: Acceptance and Commitment Therapy
Up to 10 sessions of Acceptance and Commitment Therapy plus treatment as usual
Other: Acceptance and Commitment Therapy
Up to 10 sessions of a psychological therapy called Acceptance and Commitment Therapy
Other Name: ACT
Emphasis has been placed on treating the 'positive symptoms' of psychosis (e.g. hallucinations and delusions). Concordance rates with anti-psychotic medication can be low. Even when positive symptoms are successfully treated, emotional distress can remain e.g. depression, anxiety and trauma. Relapse occurs in up to two thirds of patients within two years of the first episode. The treatment of subsequent episodes has been shown to be progressively less efficacious. Research has shown that fear of recurrence patients can experience following psychosis is predictive of relapse. Randomised clinical trials have found that Cognitive Behaviour Therapy (CBTp) is efficacious for treating residual distressing positive and negative symptoms. However, the evidence for treating emotional dysfunction (e.g. social anxiety, post-psychotic depression) is less clear. Acceptance and Commitment Therapy (ACT) incorporates acceptance and mindfulness elements into a CBT framework. Rather than altering the content or frequency of cognitions, ACT seeks to alter the individual's psychological relationship with thoughts, feelings and sensations to promote psychological flexibility. This research will be a pilot randomised control trial of ACT for treating distress following psychosis. This pilot study will establish (a) whether a larger scale multi-centre randomised controlled trial is warranted, (b) the acceptability of Acceptance and Commitment Therapy (c) the expected primary and secondary outcomes for such a trial and (d) the sample size required to detect such outcomes. It is hypothesised that ACT plus treatment as usual will be associated with a greater reduction in levels of distress than treatment as usual only.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01003132
|Greater Glasgow and Clyde NHS|
|Glasgow, Scotland, United Kingdom, G3 8YZ|
|Principal Investigator:||Ross G White, BSc, PhD, DClinPsy||University of Glasgow|