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C-Reactive Protein as a Predictor for Airway Hyper-Responsiveness

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ClinicalTrials.gov Identifier: NCT01002144
Recruitment Status : Completed
First Posted : October 27, 2009
Last Update Posted : October 27, 2009
Information provided by:
Rambam Health Care Campus

Brief Summary:
Background: Increased serum high sensitivity C-reactive protein (hs-CRP) has been associated with airway inflammation in asthma and may serve as a surrogate marker for the presence of airway hyper-responsiveness (AHR) in this set-up. This study was designed to evaluate the predictive value of hs-CRP for AHR assessed by metacholine challenge test (MCT), in adults with suspected Asthma.

Condition or disease Intervention/treatment
Asthma Other: blood sampling

Study Type : Observational
Actual Enrollment : 88 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: C-Reactive Protein as a Predictor for Airway Hyper-responsiveness
Study Start Date : March 2007
Primary Completion Date : March 2009
Study Completion Date : May 2009

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
people with suspected asthma underwent metacholine chalange test.

Inclusion Criteria:

  • subjects that were referred to Metacholine challenge test

Exclusion Criteria:

  • age < 18

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01002144

Sponsors and Collaborators
Rambam Health Care Campus
Principal Investigator: Mordechai Yigla, MD Rambam Health Care Campus

Responsible Party: the sponsor is the principal investigator, Rambam Health Care Campus
ClinicalTrials.gov Identifier: NCT01002144     History of Changes
Other Study ID Numbers: CRPAHR - CTIL
First Posted: October 27, 2009    Key Record Dates
Last Update Posted: October 27, 2009
Last Verified: October 2009

Additional relevant MeSH terms:
Respiratory Hypersensitivity
Respiratory Tract Diseases
Hypersensitivity, Immediate
Immune System Diseases