Effects of Different Mode of Exercise Training on Type 2 Diabetes
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|ClinicalTrials.gov Identifier: NCT01000519|
Recruitment Status : Completed
First Posted : October 23, 2009
Last Update Posted : February 10, 2017
|Condition or disease||Intervention/treatment||Phase|
|Diabetes Mellitus, Type 2||Other: Aerobic Training Other: Progressive resistance training||Not Applicable|
Many studies have shown the importance of aerobic training with respect to management of diabetes. However adoption of aerobic activities may be challenging for some individuals with diabetes, especially the elderly and the obese. There is increasing interest in resistance training and no study have looked at direct comparison between the two.
Subjects with diabetes but is generally sedentary (determined by means of a questionnaire) were recruited and randomized in one of the two groups. Subjects are supervised in a group and a completer is defined as one who completed 18 sessions within 8 weeks.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||60 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Investigator, Outcomes Assessor)|
|Official Title:||Differential Effects of Aerobic Versus Progressive Resistance Training on Metabolic Profile and Fitness in Older Adults With Diabetes Mellitus - a Randomized Controlled Trial|
|Study Start Date :||December 2002|
|Actual Primary Completion Date :||June 2006|
|Actual Study Completion Date :||June 2006|
Active Comparator: Aerobic Training
50 minutes of aerobic training, 18 sessions within 2 months period
Other: Aerobic Training
18 sessions over 2 months period. Each session consist of 50 minutes of aerobic training at 65-70 % of maximum predicted heart rate
Experimental: Progressive Resistance Training
50 minutes of progressive resistance training consisting of nine resistance exercises, each conducted 3 sets of 10 repetitions. 18 sessions over 2 months period.
Other: Progressive resistance training
18 sessions completed in 2 months. each session consists of 50 minutes of resistance training which is made up of 3 sets of 10 repetitions of nine resistive exercises using machines and free weights at 65-70% of 1-repetitive maximum.
- Hemoglobin A, Glycosylated (Hba1c). Measuring unit: percentage [ Time Frame: 2 months ]Blood was drawn from each subject who fasted at least 10 hours overnight. Hba1c (%) was measured using high performance liquid chromatography (HPLC Variant II Bio Rad Laboratories, Munich, Germany). Change in Hba1c before and after intervention were looked at.
- Peak volume of oxygen consumed (VO2peak) or fitness level. Measuring unit: ml/kg/min [ Time Frame: 2 months ]Modified Bruce protocol on a treadmill using Cosmed K4B2 machine to measure
- Anthropometric measurements [ Time Frame: 2 months ]weight (kilogram), height (metres), body mass index (BMI), waist circumference (centimeters) and body fat (percentage). Measurements to be taken before and after intervention.
- Cholesterol [ Time Frame: 2 months ]Blood was drawn from each subject who fasted at least 10 hours overnight. Total cholesterol and triglycerides (TG) were measured using enzymatic colorimetric methods with cholesterol oxidase-peroxidase amino phenazone phenol and glycerol-3-phospahte oxidase-peroxidase amino phenazone phenol. High-density lipoprotein cholesterol (HDL-C) was measured using homogenous enzymatic colorimetric assay. Low-density lipoprotein cholesterol (LDL-C) was calculated using the Friedewald formula.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01000519
|Singapore General Hospital|
|Singapore, Singapore, 169608|
|Principal Investigator:||Li Whye Cindy Ng||Singapore General Hospital|