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Surgical Versus Medical Treatment of Acromegaly

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ClinicalTrials.gov Identifier: NCT01000090
Recruitment Status : Completed
First Posted : October 22, 2009
Last Update Posted : December 3, 2015
Sponsor:
Information provided by (Responsible Party):
University of Aarhus

Brief Summary:

Evaluate biochemical differences in acromegalic patients treated with surgery versus somatostatin analogues (SMS) (after surgery or alone).

Hypothesis: Treatment modality exhibit different biochemical responses in acromegaly.


Condition or disease
Acromegaly

Study Type : Observational
Actual Enrollment : 63 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Surgical Versus Medical Treatment of Acromegaly: Effects on Biochemical Markers
Study Start Date : October 2009
Actual Primary Completion Date : February 2010
Actual Study Completion Date : June 2011

Resource links provided by the National Library of Medicine


Group/Cohort
Acromegaly patients, somatostain analogues
Acromegaly patients, surgery



Biospecimen Retention:   Samples Without DNA
Serum


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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Acromegalic patients followed in the outpatient clinic at Århus University Hospital, Medical Department M
Criteria

Inclusion Criteria:

  • Acromegaly diagnosis
  • treated with Somatostatin analogues or surgery
  • in treatment control

Exclusion Criteria:

  • treatment with GH-antagonist
  • never treated
  • not in treatment control

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01000090


Locations
Denmark
Århus University Hospital, Medical department M
Århus, Denmark, 8000
Sponsors and Collaborators
University of Aarhus
Investigators
Study Director: Kristine Z Rubeck, stud. med. Medical department M, Århus University Hospital
Principal Investigator: Jens Otto L Jørgensen, MD Medical department M, Århus University Hospital
Study Director: Michael Madsen, MD Medical department M, Århus University Hospital
Study Director: Sanne Fisker, MD Medical department M, Århus University Hospital
Study Director: Caroline Adreasen, MD Medical department M, Århus University Hospital
Study Director: Jan Frystyk, MD Medical department M, Århus University Hospital

Responsible Party: University of Aarhus
ClinicalTrials.gov Identifier: NCT01000090     History of Changes
Other Study ID Numbers: kzr200809
First Posted: October 22, 2009    Key Record Dates
Last Update Posted: December 3, 2015
Last Verified: June 2011

Keywords provided by University of Aarhus:
Acromegaly
Somatostatin analogues
Treatment

Additional relevant MeSH terms:
Acromegaly
Bone Diseases, Endocrine
Bone Diseases
Musculoskeletal Diseases
Hyperpituitarism
Pituitary Diseases
Hypothalamic Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Endocrine System Diseases