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Surgical Versus Medical Treatment of Acromegaly

This study has been completed.
Information provided by:
University of Aarhus Identifier:
First received: October 21, 2009
Last updated: June 22, 2011
Last verified: June 2011

Evaluate biochemical differences in acromegalic patients treated with surgery versus somatostatin analogues (SMS) (after surgery or alone).

Hypothesis: Treatment modality exhibit different biochemical responses in acromegaly.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Surgical Versus Medical Treatment of Acromegaly: Effects on Biochemical Markers

Resource links provided by NLM:

Further study details as provided by University of Aarhus:

Biospecimen Retention:   Samples Without DNA


Enrollment: 63
Study Start Date: October 2009
Study Completion Date: June 2011
Primary Completion Date: February 2010 (Final data collection date for primary outcome measure)
Acromegaly patients, somatostain analogues
Acromegaly patients, surgery


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Acromegalic patients followed in the outpatient clinic at Århus University Hospital, Medical Department M


Inclusion Criteria:

  • Acromegaly diagnosis
  • treated with Somatostatin analogues or surgery
  • in treatment control

Exclusion Criteria:

  • treatment with GH-antagonist
  • never treated
  • not in treatment control
  Contacts and Locations
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Please refer to this study by its identifier: NCT01000090

Århus University Hospital, Medical department M
Århus, Denmark, 8000
Sponsors and Collaborators
University of Aarhus
Study Director: Kristine Z Rubeck, stud. med. Medical department M, Århus University Hospital
Principal Investigator: Jens Otto L Jørgensen, MD Medical department M, Århus University Hospital
Study Director: Michael Madsen, MD Medical department M, Århus University Hospital
Study Director: Sanne Fisker, MD Medical department M, Århus University Hospital
Study Director: Caroline Adreasen, MD Medical department M, Århus University Hospital
Study Director: Jan Frystyk, MD Medical department M, Århus University Hospital
  More Information

No publications provided

Responsible Party: Jens Otto Lunde Jørgensen, Århus University Hospital Identifier: NCT01000090     History of Changes
Other Study ID Numbers: kzr200809
Study First Received: October 21, 2009
Last Updated: June 22, 2011
Health Authority: Denmark: Danish Dataprotection Agency

Keywords provided by University of Aarhus:
Somatostatin analogues

Additional relevant MeSH terms:
Bone Diseases
Bone Diseases, Endocrine
Brain Diseases
Central Nervous System Diseases
Endocrine System Diseases
Hypothalamic Diseases
Musculoskeletal Diseases
Nervous System Diseases
Pituitary Diseases processed this record on March 03, 2015