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Optimizing Resuscitation After Cardiac Arrest in the Community

This study is ongoing, but not recruiting participants.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00998140
First Posted: October 20, 2009
Last Update Posted: April 28, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Dr Sharon Einav, Shaare Zedek Medical Center
  Purpose

Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage. Time to efficacious care is a primary determinant of disability-free survival. In the Jerusalem district, only 9% of OHCA patients present with ventricular tachycardia/ventricular fibrillation (VT/VF) as the primary rhythm, whereas 77% present with asystole; this seems primarily to be the result of long collapse-to-arrival times. Nevertheless, overly zealous resuscitation is undertaken in a high proportion of arrests with a futile prognosis, leading to excessive costs.

Study hypotheses:

  1. Subpopulations for whom intervention is futile/counter-productive are identifiable
  2. Substantial waste of resources can be avoided
  3. Optimization of emergency medical services (EMS) reorganization without adding resources is an achievable goal

Condition
Cardiopulmonary Arrest Outcome

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Other
Official Title: Optimizing Resuscitation After Cardiac Arrest in the Community: Increasing the Probability of Survival While Reducing Costs

Resource links provided by NLM:


Further study details as provided by Dr Sharon Einav, Shaare Zedek Medical Center:

Estimated Enrollment: 1600
Study Start Date: March 2009
Estimated Study Completion Date: March 2020
Estimated Primary Completion Date: September 2019 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.
Criteria

Inclusion Criteria:

  • All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.

Exclusion Criteria:

  • Patients with do-not-resuscitate orders or an advance directive to that effect.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00998140


Locations
Israel
Shaare Zedek Medical Center
Jerusalem, Israel
Sponsors and Collaborators
Shaare Zedek Medical Center
Investigators
Principal Investigator: Sharon Einav, MD Shaare Zedek Medical Center
  More Information

Publications:
Responsible Party: Dr Sharon Einav, Dr., Shaare Zedek Medical Center
ClinicalTrials.gov Identifier: NCT00998140     History of Changes
Other Study ID Numbers: NIHPR 08/90/a
First Submitted: October 18, 2009
First Posted: October 20, 2009
Last Update Posted: April 28, 2017
Last Verified: April 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Yes

Keywords provided by Dr Sharon Einav, Shaare Zedek Medical Center:
resuscitation
sudden death
cardiopulmonary resuscitation
emergency medical services
termination of resuscitation
ventricular fibrillation
out-of-hospital cardiac arrest
asystole
medical futility
withdrawing treatment
transportation of patients
health expenditures
healthcare costs

Additional relevant MeSH terms:
Heart Arrest
Heart Diseases
Cardiovascular Diseases


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