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Optimizing Resuscitation After Cardiac Arrest in the Community

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2011 by Shaare Zedek Medical Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Shaare Zedek Medical Center
ClinicalTrials.gov Identifier:
NCT00998140
First received: October 18, 2009
Last updated: May 17, 2011
Last verified: May 2011
History of Changes
  Purpose

Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage. Time to efficacious care is a primary determinant of disability-free survival. In the Jerusalem district, only 9% of OHCA patients present with ventricular tachycardia/ventricular fibrillation (VT/VF) as the primary rhythm, whereas 77% present with asystole; this seems primarily to be the result of long collapse-to-arrival times. Nevertheless, overly zealous resuscitation is undertaken in a high proportion of arrests with a futile prognosis, leading to excessive costs.

Study hypotheses:

  1. Subpopulations for whom intervention is futile/counter-productive are identifiable
  2. Substantial waste of resources can be avoided
  3. Optimization of emergency medical services (EMS) reorganization without adding resources is an achievable goal

Condition
Cardiopulmonary Arrest Outcome

Study Type: Observational
Study Design: Observational Model: Cohort
Official Title: Optimizing Resuscitation After Cardiac Arrest in the Community: Increasing the Probability of Survival While Reducing Costs

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Shaare Zedek Medical Center:
Estimated Enrollment: 1600
Study Start Date: March 2009
Estimated Study Completion Date: March 2012
  Eligibility
Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.

Criteria

Inclusion Criteria:

  • All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district.

Exclusion Criteria:

  • Patients with do-not-resuscitate orders or an advance directive to that effect.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00998140

Contacts
Contact: Sharon Einav, MD 972-508-685-480 einav_s@szmc.org.il
Contact: Nechama Kaufman, MN 972-508-685-324 kaufman_n@hotmail.com

Locations
Israel
Shaare Zedek Medical Center Recruiting
Jerusalem, Israel
Principal Investigator: Sharon Einav, MD         
Sponsors and Collaborators
Shaare Zedek Medical Center
Investigators
Principal Investigator: Sharon Einav, MD Shaare Zedek Medical Center
  More Information

No publications provided

Responsible Party: Sharon Einav, MD, Director of Surgical ICU, Shaare Zedek Medical Center
ClinicalTrials.gov Identifier: NCT00998140     History of Changes
Other Study ID Numbers: NIHPR 08/90/a
Study First Received: October 18, 2009
Last Updated: May 17, 2011
Health Authority: Israel: Ministry of Health

Keywords provided by Shaare Zedek Medical Center:
out-of-hospital cardiac arrest
asystole
resuscitation
sudden death
cardiopulmonary resuscitation
emergency medical services
termination of resuscitation
 ventricular fibrillation
medical futility
withdrawing treatment
transportation of patients
health expenditures
healthcare costs

ClinicalTrials.gov processed this record on February 27, 2015