An Exploration of Genetic Testing for Prostate Cancer Susceptibility
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ClinicalTrials.gov Identifier: NCT00997464
Recruitment Status : Unknown
Verified October 2009 by Royal Marsden NHS Foundation Trust. Recruitment status was: Recruiting
Study of the factors that affect interest in - and uptake of - genetic testing for variants that predispose to prostate cancer from the perspective of the patient.
Condition or disease
This study will use a mixed methods approach to follow men as they move through the genetic testing process, from initial contact through to receiving their genetic testing results. A questionnaire will be used to measure variables at both baseline and after proceeding through the testing process. A small cohort of men will be invited to be interviewed to gather some in depth qualitative data about the issues that have arisen during the study process.
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Ages Eligible for Study:
40 Years to 69 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Men with strong family history of prostate cancer.
Men with a positive family history of prostate cancer. The definition of a positive family history will be: Men with a first degree relative with prostate cancer diagnosed at <70 years; Men with two relatives with prostate cancer where at least on is diagnosed at <70 years; Men with three relatives with prostate cancer diagnosed at any age
Age 40-69 years
No previous biopsy for raised PSA
Absence of any psychological, familial, sociological or geographic situation potentially hampering compliance with the study protocol and follow-up schedule.
Previous prostate cancer
Men from families where there is known to be a mutation in a high-risk prostate cancer gene
Men who have had a prostate biopsy within the last 12 months.