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Biomarkers for Bipolar Disorder: Chaperones and Reticulum Endoplasmatic Stress Response CHAP´s Study (CHAPS)

This study has suspended participant recruitment.
(fail to get funding)
Sponsor:
ClinicalTrials.gov Identifier:
NCT00994630
First Posted: October 14, 2009
Last Update Posted: August 16, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Sao Paulo
  Purpose

The purpose of this study is to determine expression of chaperones proteins from the endoplasmatic reticulum stress response system in bipolar I patients (manic phase) compared to healthy controls.

Hypothesis: There is no difference in chaperones proteins expression between bipolar I manic patients and healthy controls


Condition
Bipolar Disease Type I

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Biomarkers for Bipolar Disorder: Chaperones and Reticulum Endoplasmatic Stress Response CHAP´s Study

Resource links provided by NLM:


Further study details as provided by University of Sao Paulo:

Biospecimen Retention:   Samples With DNA
Dna and Rna analysis

Estimated Enrollment: 20
Study Start Date: January 2010
Estimated Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
BP I patients manic phase

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 55 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Bipolar Disease type I manic phase
Criteria

Inclusion Criteria:

  • Bipolar Disease type I manic phase
  • YMRS > 14
  • HDRS < 9

Exclusion Criteria:

  • Use of lithium, divalproate, or carbamazepine in therapeutic levels over the past 30 days
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00994630


Locations
Brazil
Mood Disorders Program, Institute of Psychiatry, Faculty of Medicine, University of Sao Paulo
Sao paulo, Brazil
Sponsors and Collaborators
University of Sao Paulo
Investigators
Principal Investigator: Ricardo A Moreno, MD, PhD Mood Disorders Program, Institute of Psychiatry, Faculty of Medicine, University of Sao Paulo, Brazil
Study Director: Marcio G Soeiro de Souza, MD Mood Disorders Program, Institute of Psychiatry, Faculty of Medicine, University of Sao Paulo, Brazil
  More Information

Responsible Party: Ricardo Alberto Moreno, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT00994630     History of Changes
Other Study ID Numbers: CHAPS STUDY
First Submitted: October 13, 2009
First Posted: October 14, 2009
Last Update Posted: August 16, 2011
Last Verified: May 2011

Additional relevant MeSH terms:
Bipolar Disorder
Bipolar and Related Disorders
Mental Disorders