Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Study of Oral Papillomavirus In Teens and Twenties (SPITT)

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Gypsyamber D'Souza, Johns Hopkins Bloomberg School of Public Health Identifier:
First received: October 13, 2009
Last updated: May 1, 2013
Last verified: May 2013

Recently human papillomavirus (HPV) has been recognized to cause some oropharyngeal (tonsil) cancer. But very little is known about oral HPV infection and risk factors. This study will evaluate how common oral HPV infection is, what sexual behaviors are associated with risk for infection, and how long infections tend to last.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Short-term Natural History of Oral HPV Infection Among Young Adults

Resource links provided by NLM:

Further study details as provided by Johns Hopkins Bloomberg School of Public Health:

Primary Outcome Measures:
  • Oral HPV infection [ Time Frame: 24 months ] [ Designated as safety issue: No ]
    Oral rinse samples collected prospectively for 24 months

Enrollment: 550
Study Start Date: January 2010
Estimated Study Completion Date: May 2014
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Detailed Description:

18-25 year old individuals are being recruited from STD clinics in Baltimore County and followed every three months for this study.


Ages Eligible for Study:   18 Years to 26 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

High risk young adults


Inclusion Criteria:

  • Age 18 -26 years

Exclusion Criteria:

  • Never received HPV vaccine (Gardasil or Cervarix)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00994019

United States, Maryland
Baltimore County Eastern Health Center
Baltimore, Maryland, United States, 21237
Baltimore County Woodlawn Health Centers
Baltimore, Maryland, United States, 21207
Sponsors and Collaborators
Johns Hopkins Bloomberg School of Public Health
Principal Investigator: Gypsyamber D'Souza, PhD Johns Hopkins School of Public Health
  More Information

No publications provided

Responsible Party: Gypsyamber D'Souza, Associate Professor, Johns Hopkins Bloomberg School of Public Health Identifier: NCT00994019     History of Changes
Other Study ID Numbers: 2422
Study First Received: October 13, 2009
Last Updated: May 1, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by Johns Hopkins Bloomberg School of Public Health:
oral cancer
young adults processed this record on February 27, 2015