Mechanisms Defending Fat Mass in Humans After Lipectomy
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00993213|
Recruitment Status : Completed
First Posted : October 12, 2009
Last Update Posted : December 6, 2016
|Condition or disease||Intervention/treatment||Phase|
|Disproportionate Shape Expanded Fat Pads||Procedure: Standard of Care with Liposuction Other: Standard of Care without Liposuction||Not Applicable|
- To determine if suction lipectomy fails to modify regional and/or total body fat over three years.
- To determine if the expression of candidate genes predicts and/or relates to subcutaneous adipose tissue growth or depletion in subcutaneous adipose tissue after suction lipectomy.
- To examine adipose tissue before and after suction lipectomy to uncover novel genes where expression predicts and/or relates to subcutaneous adipose tissue growth or depletion after subcutaneous suction lipectomy.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||32 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Mechanisms Defending Fat Mass in Humans After Lipectomy|
|Study Start Date :||April 2004|
|Actual Primary Completion Date :||November 2008|
|Actual Study Completion Date :||November 2008|
Active Comparator: Liposuction
Standard of Care with Liposuction
Procedure: Standard of Care with Liposuction
Standard of Care encompasses body composition measurements, a euglycemic clamp and fat biopsies, followed by Liposuction surgery.
Sham Comparator: No Liposuction
Standard of Care without Liposuction'
Other: Standard of Care without Liposuction
Standard of Care encompasses body composition measurements, a euglycemic clamp and fat biopsies. Liposuction surgery will not be performed.
- Changes in body composition. [ Time Frame: Baseline, 6wks, 6mos, 1-year ]Changes in body composition as measured by Dual X-ray Absorptiometry (DXA).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00993213
|United States, Colorado|
|University of Colorado Denver|
|Aurora, Colorado, United States, 80045|
|Principal Investigator:||Robert H Eckel, MD||University of Colorado, Denver|