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Creatine Supplementation and Diabetes

This study has been completed.
Information provided by:
University of Sao Paulo Identifier:
First received: October 7, 2009
Last updated: March 22, 2010
Last verified: October 2009
Creatine supplementation is capable of improving glucose tolerance in healthy subjects. The researchers aim to investigate whether this supplement can affect metabolic control in diabetic patients.

Condition Intervention
Diabetes Renal Function Dietary Supplement: creatine Other: Exercise training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Care Provider, Investigator)
Primary Purpose: Treatment
Official Title: Efficacy and Safety of Creatine Supplementation Combined With Exercise Training in Type 2 Diabetic Patients

Resource links provided by NLM:

Further study details as provided by University of Sao Paulo:

Primary Outcome Measures:
  • glycated hemoglobin [ Time Frame: three months ]

Enrollment: 28
Study Start Date: October 2009
Study Completion Date: January 2010
Arms Assigned Interventions
Placebo Comparator: exercise and placebo Dietary Supplement: creatine Other: Exercise training
Experimental: exercise and creatine Dietary Supplement: creatine Other: Exercise training


Ages Eligible for Study:   45 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • males and females type 2 diabetic patients
  • glycated hemoglobin between > 9%
  • non insulin users
  • physically inactive
  • only metformin and/or sulfonylurea users
  • BMI > 30 kg/m2
  • age of years > 50 y
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Please refer to this study by its identifier: NCT00992043

General Hospital - School of Medicine - University of Sao Paulo
Sao Paulo, Brazil, 05508-030
Sponsors and Collaborators
University of Sao Paulo
Principal Investigator: Bruno Gualano, PhD ongoing University of Sao Paulo