Creatine Supplementation and Diabetes

This study has been completed.
Information provided by:
University of Sao Paulo Identifier:
First received: October 7, 2009
Last updated: March 22, 2010
Last verified: October 2009
Creatine supplementation is capable of improving glucose tolerance in healthy subjects. The researchers aim to investigate whether this supplement can affect metabolic control in diabetic patients.

Condition Intervention
Renal Function
Dietary Supplement: creatine
Other: Exercise training

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator)
Primary Purpose: Treatment
Official Title: Efficacy and Safety of Creatine Supplementation Combined With Exercise Training in Type 2 Diabetic Patients

Resource links provided by NLM:

Further study details as provided by University of Sao Paulo:

Primary Outcome Measures:
  • glycated hemoglobin [ Time Frame: three months ] [ Designated as safety issue: No ]

Enrollment: 28
Study Start Date: October 2009
Study Completion Date: January 2010
Arms Assigned Interventions
Placebo Comparator: exercise and placebo Dietary Supplement: creatine Other: Exercise training
Experimental: exercise and creatine Dietary Supplement: creatine Other: Exercise training


Ages Eligible for Study:   45 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • males and females type 2 diabetic patients
  • glycated hemoglobin between > 9%
  • non insulin users
  • physically inactive
  • only metformin and/or sulfonylurea users
  • BMI > 30 kg/m2
  • age of years > 50 y
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Please refer to this study by its identifier: NCT00992043

General Hospital - School of Medicine - University of Sao Paulo
Sao Paulo, Brazil, 05508-030
Sponsors and Collaborators
University of Sao Paulo
Principal Investigator: Bruno Gualano, PhD ongoing University of Sao Paulo
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Bruno Gualano, University of Sao Paulo Identifier: NCT00992043     History of Changes
Other Study ID Numbers: eefeusp2 
Study First Received: October 7, 2009
Last Updated: March 22, 2010
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by University of Sao Paulo:
creatine supplementation
exercise training processed this record on May 25, 2016