Plaque Registration and Event Detection In Computed Tomography (PREDICT)
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ClinicalTrials.gov Identifier: NCT00991835
Recruitment Status : Unknown
Verified March 2013 by Yasuki Kihara, Hiroshima University. Recruitment status was: Active, not recruiting
Disruption of an atherosclerotic plaque is responsible for at least two-thirds of acute coronary syndrome. Thus, identification of plaques vulnerable to rupture has become important. The natural history of individual plaques is unknown and needs to be established. Multidetector computed tomography (MDCT) angiography is a useful noninvasive imaging modality for assessing coronary plaque characteristics. Using MDCT, the researchers prospectively investigate the relationship between the characterization of coronary plaques and cardiovascular events in a large multicenter study.
Prospective Multicenter Study to Investigate the Relationship Between the Characteristics of Coronary Artery Plaques and Cardiovascular Events Using Multidetector Computed Tomography Coronary Angiography
Study Start Date :
Actual Primary Completion Date :
Estimated Study Completion Date :
Resource links provided by the National Library of Medicine
Major cardiac events (Cardiac death and acute coronary syndrome) [ Time Frame: 2 years after the CT-scan ]
All-cause death [ Time Frame: 2 years after the CT-scan ]
Secondary Outcome Measures :
All coronary events (Cardiac death, non-fatal MI, unstable angina requiring hospitalization, late coronary revascularizations) [ Time Frame: 2 years after CT-scan ]
All cardiovascular events (Death, acute coronary syndrome, heart failure, cerebral disease, peripheral artery disease, aortic disease, and renal failure) [ Time Frame: 2 years after the CT-scan ]
Other Outcome Measures:
Coronary plaque progression and managements for serum cholesterol, blood glucose, renal function and blood pressure: Especially impacts of statin on the changes in coronary plaque characteristics [ Time Frame: 2 years after CT ]
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Ages Eligible for Study:
20 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
patients reffered to cardiovascular hospital
patients with known or suspected coronary artery disease.
irregular heart beat,
known allergy towards the contrast agent,
uncontrolled heart failure,
previous coronary bypass surgery, or pacemaker or ICD implantation, ST elevation MI or unstable hemodynamic condition,