Long Term Vascular Changes in Type 1 Diabetes (DM09)
|ClinicalTrials.gov Identifier: NCT00991575|
Recruitment Status : Unknown
Verified October 2009 by Oslo University Hospital.
Recruitment status was: Enrolling by invitation
First Posted : October 8, 2009
Last Update Posted : October 8, 2009
|Condition or disease|
|Diabetes Mellitus, Type 1 Complications Coronary Heart Disease|
Despite intensively research in the field of hyperglycaemia and coronary heart disease in type 1 diabetes it is still not known in detail how hyperglycaemia leads to damage of the vessels.
The aims of the present proposal are therefore two-fold:
- To study in detail the progression of atherosclerosis (and micro vascular complications) in a well characterized cohort of type 1 diabetes with a long duration of the disease. This project will be a continuation of the Oslo study, a cohort started in 1982, with the last follow-up study in 1999/2000.
- To define factors responsible for the progression of coronary heart disease (and micro vascular complications) in this cohort.
|Study Type :||Observational|
|Estimated Enrollment :||45 participants|
|Official Title:||Long Term Vascular Changes in Type 1 Diabetes, Clinical Aspects and Biological Markers|
|Study Start Date :||April 2009|
|Estimated Primary Completion Date :||April 2010|
|Estimated Study Completion Date :||May 2010|
|Diabetes, type 1|
- Fatal and non fatal cardiovascular disease (CVD) and stroke [ Time Frame: One year ]
- Vessel area stenosis [ Time Frame: One year ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00991575
|Oslo University hospital, Aker|
|Oslo, Norway, 0514|
|Principal Investigator:||Kristian F Hanssen, Professor MD||Oslo university hospital, Aker, Norway|