The Effect of Whey Protein on Short-Term Food Intake and Post-Meal Blood Glucose Response in Young Men

This study has been completed.

Sponsor:

Collaborators:

Natural Sciences and Engineering Research Council, Canada

Mondelēz International, Inc.

Information provided by:

University of Toronto

ClinicalTrials.gov Identifier:

NCT00988377

First received: September 30, 2009

Last updated: October 1, 2009

Last verified: October 2009

History of Changes

Purpose

The objective of this study was to describe relationships among whey protein when consumed before a meal on food intake and pre- and post-meal satiety, blood glucose in healthy young adults.

Condition	Intervention
Diabetes Prevention Obesity Prevention	Other: dietary intervention Other: water control


Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Crossover Assignment Masking: Single Blind (Subject) Primary Purpose: Prevention
Official Title:	The Effect of Whey Protein on Short-term Food Intake and Post-meal Blood Glucose Response in Young Men

Resource links provided by NLM:

MedlinePlus related topics: Blood Sugar Drinking Water

U.S. FDA Resources

Further study details as provided by University of Toronto:

Primary Outcome Measures:

Blood glucose subjective appetite Food intake at 30 min [ Time Frame: 0-95 min ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

physical comfort palatability [ Time Frame: 0-95 min ] [ Designated as safety issue: No ]


Enrollment:	16
Study Start Date:	May 2007
Study Completion Date:	November 2007
Primary Completion Date:	August 2007 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: 10 g whey protein	Other: dietary intervention whey protein 10-40 g
Experimental: 20 g whey protein	Other: dietary intervention whey protein 10-40 g
Experimental: 30 g whey protein	Other: dietary intervention whey protein 10-40 g
Experimental: 40 g whey protein	Other: dietary intervention whey protein 10-40 g
Experimental: water control Iso-volumetric (300 ml) water control (Crystal Springs, Canada)	Other: water control Iso-volumetric (300 ml) water control (Crystal Springs, Canada)

Detailed Description:

A randomized, cross-over design study was conducted. Whey protein preloads (10-40 g) were provided in 300 ml water. At 30 min following consumption, subjects were fed an ad libitum pizza meal. Satiety, and blood glucose were measured at baseline and selected intervals pre- (0, 15 and 30 min) and post-meal (50, 65, 80 and 95 min).

Eligibility


Ages Eligible for Study:	20 Years to 27 Years (Adult)
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

healthy
normal weight ( 18-24.9 kg/m²)
young aged 20-27 year old

Exclusion Criteria:

breakfast skippers
smokers
dieters
individuals with diabetes (fasting BG ≥ 7.0 mmol/L) or other metabolic diseases

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00988377

Locations


Canada, Ontario
University of Toronto, Department of Nutritional Sciences
Toronto, Ontario, Canada, M5S 3E2

Sponsors and Collaborators

University of Toronto

Natural Sciences and Engineering Research Council, Canada

Mondelēz International, Inc.

Investigators


Principal Investigator:	Harvey Anderson, Ph.D.	University of Toronto

More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Akhavan T, Luhovyy BL, Brown PH, Cho CE, Anderson GH. Effect of premeal consumption of whey protein and its hydrolysate on food intake and postmeal glycemia and insulin responses in young adults. Am J Clin Nutr. 2010 Apr;91(4):966-75. doi: 10.3945/ajcn.2009.28406. Epub 2010 Feb 17.


Responsible Party:	Dr. G. Harvey Anderson, University of Toronto
ClinicalTrials.gov Identifier:	NCT00988377 History of Changes
Other Study ID Numbers:	Kraft_whey protein: study 1
Study First Received:	September 30, 2009
Last Updated:	October 1, 2009
Health Authority:	Canada: Ethics Review Committee

Keywords provided by University of Toronto:


whey protein subjective appetite shor-term food intake blood glucose

ClinicalTrials.gov processed this record on September 27, 2016

To Top