ClinicalTrials.gov
ClinicalTrials.gov Menu

The Effect of Whey Protein on Short-Term Food Intake and Post-Meal Blood Glucose Response in Young Men

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00988377
Recruitment Status : Completed
First Posted : October 2, 2009
Last Update Posted : October 2, 2009
Sponsor:
Collaborators:
Natural Sciences and Engineering Research Council, Canada
Mondelēz International, Inc.
Information provided by:
University of Toronto

Study Description
Go to 
Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information
Brief Summary:
The objective of this study was to describe relationships among whey protein when consumed before a meal on food intake and pre- and post-meal satiety, blood glucose in healthy young adults.

Condition or disease Intervention/treatment Phase
Diabetes Prevention Obesity Prevention Other: dietary intervention Other: water control Not Applicable

Detailed Description:
A randomized, cross-over design study was conducted. Whey protein preloads (10-40 g) were provided in 300 ml water. At 30 min following consumption, subjects were fed an ad libitum pizza meal. Satiety, and blood glucose were measured at baseline and selected intervals pre- (0, 15 and 30 min) and post-meal (50, 65, 80 and 95 min).

Study Design
Go to 
Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 16 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Prevention
Official Title: The Effect of Whey Protein on Short-term Food Intake and Post-meal Blood Glucose Response in Young Men
Study Start Date : May 2007
Actual Primary Completion Date : August 2007
Actual Study Completion Date : November 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Blood Sugar

Arms and Interventions
Go to 
Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Arm Intervention/treatment
Experimental: 10 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: 20 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: 30 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: 40 g whey protein Other: dietary intervention
whey protein 10-40 g
Experimental: water control
Iso-volumetric (300 ml) water control (Crystal Springs, Canada)
 Other: water control
Iso-volumetric (300 ml) water control (Crystal Springs, Canada)


Outcome Measures
Go to 
Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Primary Outcome Measures :
  1. Blood glucose subjective appetite Food intake at 30 min [ Time Frame: 0-95 min ]

Secondary Outcome Measures :
  1. physical comfort palatability [ Time Frame: 0-95 min ]

Eligibility Criteria
Go to 
Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   20 Years to 27 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy
  • normal weight ( 18-24.9 kg/m²)
  • young aged 20-27 year old

Exclusion Criteria:

  • breakfast skippers
  • smokers
  • dieters
  • individuals with diabetes (fasting BG ≥ 7.0 mmol/L) or other metabolic diseases
Contacts and Locations
Go to 
Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00988377


Locations
Canada, Ontario
University of Toronto, Department of Nutritional Sciences
Toronto, Ontario, Canada, M5S 3E2
Sponsors and Collaborators
University of Toronto
Natural Sciences and Engineering Research Council, Canada
Mondelēz International, Inc.
Investigators
Principal Investigator: Harvey Anderson, Ph.D. University of Toronto
More Information
Go to 
Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Responsible Party: Dr. G. Harvey Anderson, University of Toronto
ClinicalTrials.gov Identifier: NCT00988377     History of Changes
Other Study ID Numbers: Kraft_whey protein: study 1
First Posted: October 2, 2009    Key Record Dates
Last Update Posted: October 2, 2009
Last Verified: October 2009

Keywords provided by University of Toronto:
whey protein
subjective appetite
shor-term food intake
blood glucose