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Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression

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ClinicalTrials.gov Identifier: NCT00987571
Recruitment Status : Completed
First Posted : October 1, 2009
Last Update Posted : October 1, 2009
Sponsor:
Information provided by:

Study Description
Brief Summary:
Carpal tunnel syndrome is caused by compression of the median nerve at the wrist. The hypothesis is that ultrasound imaging can be used to visualize nerve compression in carpal tunnel patients during hand activity, and normal subjects will not demonstrate any nerve compression.

Condition or disease
Carpal Tunnel Syndrome

Detailed Description:
Two patients with carpal tunnel syndrome underwent nerve testing to document that they had median nerve abnormality at the wrist. They subsequently had ultrasound imaging of the wrist at rest and during a stress test using hand activity. Two control subjects had nerve testing to prove that they had no nerve abnormality at the carpal tunnel. The carpal tunnel syndrome patients demonstrated nerve compression on the ultrasound images during the stress tests and the normal subjects showed no nerve compression.

Study Design

Study Type : Observational
Actual Enrollment : 4 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression
Study Start Date : April 2009
Primary Completion Date : September 2009
Study Completion Date : September 2009


Groups and Cohorts

Group/Cohort
Carpal Tunnel patients
These patients have documented carpal tunnel syndrome
Normal Subjects
These individuals have no carpal tunnel syndrome


Outcome Measures

Primary Outcome Measures :
  1. Median nerve compressive narrowing on ultrasound imaging in carpal tunnel syndrome patients [ Time Frame: 5 months ]

Secondary Outcome Measures :
  1. No median nerve compressive narrowing in normal subjects [ Time Frame: 5 months ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Adult patients with upper extremity symptoms of pain, numbness, and tingling; Adult subjects with no upper extremity pain, numbness, or tingling
Criteria

Inclusion Criteria:

  • Patients must have symptoms consistent with carpal tunnel syndrome and electrodiagnostic testing that demonstrates abnormal median nerve function at the wrist, consistent with carpal tunnel syndrome.
  • Normal subjects must have no upper limb symptoms to support carpal tunnel syndrome and normal nerve testing.

Exclusion Criteria:

  • Patients excluded if nerve testing was not consistent with carpal tunnel syndrome.
  • Normals excluded if nerve testing demonstrated any median nerve abnormality.
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00987571


Sponsors and Collaborators
EMG Labs of Arizona Arthritis & Rheumatology Associates
Investigators
Principal Investigator: Benjamin M Sucher, DO EMG Labs of AARA
More Information

Responsible Party: Benjamin M. Sucher, D.O./Medical Director, EMG Labs of AARA
ClinicalTrials.gov Identifier: NCT00987571     History of Changes
Other Study ID Numbers: CTS-US Med N JAOA
First Posted: October 1, 2009    Key Record Dates
Last Update Posted: October 1, 2009
Last Verified: September 2009

Keywords provided by EMG Labs of Arizona Arthritis & Rheumatology Associates:
carpal tunnel syndrome
median nerve
ultrasound
electrodiagnosis
Normal subjects

Additional relevant MeSH terms:
Carpal Tunnel Syndrome
Syndrome
Disease
Pathologic Processes
Median Neuropathy
Mononeuropathies
Peripheral Nervous System Diseases
Neuromuscular Diseases
Nervous System Diseases
Nerve Compression Syndromes
Cumulative Trauma Disorders
Sprains and Strains
Wounds and Injuries