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Extravascular Lung Water Index in Severe Sepsis (EVLI in sepsis)

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ClinicalTrials.gov Identifier: NCT00986271
Recruitment Status : Completed
First Posted : September 29, 2009
Last Update Posted : September 29, 2009
Sponsor:
Information provided by:
Chang Gung Memorial Hospital

Study Description
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Brief Summary:
To investigate whether extravascular lung water index (EVLI) is an independent predictor for multiorgan dysfunction syndrome (MODS) in patients with severe sepsis and to determine if increased EVLI may serve as an predictor for MODS and mortality in those patients.

Condition or disease Intervention/treatment Phase
Severe Sepsis Procedure: EVLI was determinated by PiCCO plus system. Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 67 participants
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Sepsis
U.S. FDA Resources

Arms and Interventions
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Arm Intervention/treatment
With and without MODS developement
EVLI was determinated by PiCCO plus system.
 Procedure: EVLI was determinated by PiCCO plus system.


Outcome Measures
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Primary Outcome Measures :
  1. Developement of MODS (multiorgan dysfunction syndrome) and mortality

Eligibility Criteria
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • All enrolled patients were recruited consecutively on the day of MICU admission and within 24 hours of the diagnosis of severe sepsis.

Exclusion Criteria:

  • Pregnancy,
  • Age less than 18 years old, and
  • Uncontrolled malignancy.
Contacts and Locations
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

No Contacts or Locations Provided
More Information
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

ClinicalTrials.gov Identifier: NCT00986271     History of Changes
Other Study ID Numbers: 97-0374B
First Posted: September 29, 2009    Key Record Dates
Last Update Posted: September 29, 2009
Last Verified: April 2008

Keywords provided by Chang Gung Memorial Hospital:
severe sepsis, intensive care units

Additional relevant MeSH terms:
Sepsis
Infection
Systemic Inflammatory Response Syndrome
Inflammation
Pathologic Processes