ClinicalTrials.gov
ClinicalTrials.gov Menu

Extravascular Lung Water Index in Severe Sepsis (EVLI in sepsis)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00986271
Recruitment Status : Completed
First Posted : September 29, 2009
Last Update Posted : September 29, 2009
Sponsor:
Information provided by:
Chang Gung Memorial Hospital

Brief Summary:
To investigate whether extravascular lung water index (EVLI) is an independent predictor for multiorgan dysfunction syndrome (MODS) in patients with severe sepsis and to determine if increased EVLI may serve as an predictor for MODS and mortality in those patients.

Condition or disease Intervention/treatment Phase
Severe Sepsis Procedure: EVLI was determinated by PiCCO plus system. Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 67 participants
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Sepsis
U.S. FDA Resources

Arm Intervention/treatment
With and without MODS developement
EVLI was determinated by PiCCO plus system.
Procedure: EVLI was determinated by PiCCO plus system.



Primary Outcome Measures :
  1. Developement of MODS (multiorgan dysfunction syndrome) and mortality


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Criteria

Inclusion Criteria:

  • All enrolled patients were recruited consecutively on the day of MICU admission and within 24 hours of the diagnosis of severe sepsis.

Exclusion Criteria:

  • Pregnancy,
  • Age less than 18 years old, and
  • Uncontrolled malignancy.

ClinicalTrials.gov Identifier: NCT00986271     History of Changes
Other Study ID Numbers: 97-0374B
First Posted: September 29, 2009    Key Record Dates
Last Update Posted: September 29, 2009
Last Verified: April 2008

Keywords provided by Chang Gung Memorial Hospital:
severe sepsis, intensive care units

Additional relevant MeSH terms:
Sepsis
Infection
Systemic Inflammatory Response Syndrome
Inflammation
Pathologic Processes