Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma
The purpose of this study is to evaluate the efficacy of pdt in treatment of bcc and factors that affect response rate.
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma|
- Clinical Response to Photodynamic Therapy [ Time Frame: immediately after termination of treatment course (with an average of 5 month after initiation of PDT) ] [ Designated as safety issue: Yes ]
- Histologic Resolution of Lesion [ Time Frame: immediately after the terminaton of treatment course (with an average of 5 months after initiation of PDT) ] [ Designated as safety issue: Yes ]
|Study Start Date:||January 2008|
|Study Completion Date:||March 2009|
|Primary Completion Date:||July 2008 (Final data collection date for primary outcome measure)|
Experimental: BCC, ALA-PDT
Patients with histologically proven basal cell carcinoma who were candidates for treatment with ALA-PDT
Radiation: photodynamic therapy
treatment of bcc with 5_ALA cream 20% topical administration once monthly+ photodynamic therapy (red light) 120 j/cm2 once monthly
Other Name: PDT 1200L Waldman Medizintechnik; Schwenningen, Germany
Background and Aim: Basal cell carcinoma (BCC) is the most common skin cancer .Photodynamic therapy _as a novel , non-invasive therapeutic approach _may be considered a valuable strategy. This study was designed with the aim of the evaluation of efficacy of PDT in treatment of BCC and factors that may affect response rate.
Materials and Methods: This was a clinical trial which was done on 28 BCCs. Patients were treated with ALA-PDT monthly for 1-6 sessions and evaluated for clinical response,cosmetic results and probable side effects.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00985829
|Principal Investigator:||Zohreh Tehranchi-nia, assist.prof.||Skin Research Center|