Cerebral Autoregulation Monitoring During Cardiac Surgery
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00981474|
Recruitment Status : Recruiting
First Posted : September 22, 2009
Last Update Posted : March 13, 2017
|Condition or disease||Intervention/treatment|
|Thoracic Surgery Cardiopulmonary Bypass||Drug: blood pressure maintenance based on cerebral blood flow autoregulation measurement Drug: Control group|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||490 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Outcomes Assessor)|
|Official Title:||Continuous Cerebral Autoregulation Monitoring to Reduce Brain Injury From Cardiac Surgery|
|Actual Study Start Date :||September 1, 2009|
|Estimated Primary Completion Date :||June 1, 2019|
|Estimated Study Completion Date :||August 31, 2019|
Active Comparator: Control
Blood pressure targets during cardiopulmonary bypass based on institutional standards of empiric management.
Drug: Control group
Institutional standard of care.
Blood pressure management based on cerebral autoregulation data.
Drug: blood pressure maintenance based on cerebral blood flow autoregulation measurement
Blood pressure lowered or raised
- Composite neurological outcome of clinical stroke or new ischemic brain lesion on diffusion weighted MRI or neurocognitive dysfunction 4 to 6 weeks after surgery. [ Time Frame: Perioperative ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00981474
|Contact: Charles W Hogue, MDfirstname.lastname@example.org|
|United States, Maryland|
|The Johns Hopkins Hospital||Recruiting|
|Baltimore, Maryland, United States, 21287|
|Contact: Shannon Ledroux, BSN 410-955-8567 email@example.com|
|Principal Investigator: Charles W. Hogue, MD|