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The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure

This study has been completed.
Information provided by:
Armed Forces Capital Hospital, Republic of Korea Identifier:
First received: September 21, 2009
Last updated: April 7, 2010
Last verified: April 2010
The aim is to evaluate the time of positive conversion after exposure to smear positive pulmonary tuberculosis (TB) in a platoon of Korean military, a closed communal setting.


Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure

Resource links provided by NLM:

Further study details as provided by Armed Forces Capital Hospital, Republic of Korea:

Enrollment: 32
Study Start Date: May 2009
Study Completion Date: April 2010
Primary Completion Date: April 2010 (Final data collection date for primary outcome measure)
A platoon with TB outbreak

Detailed Description:
In a platoon where TB outbreak occurred, we performed low dose chest CT (LDCT), QuantiFERON-TB gold in tube (QFT) and two-step (0, 4weeks) TST for outbreak investigation. We perform QFT at 0, 2, 4, 8 and 12 weeks after initial investigation for soldiers with negative QFT results, and soldiers with positive QFT and normal LDCT took isoniazid and rifampin for 3 months as treatment of latent TB.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
A military unit in South Korean Army

Inclusion Criteria:

  • All soldiers who assigned to the military platoon where a tuberculosis outbreak occurred

Exclusion Criteria:

  • Soldiers who could not complete study or refused the study protocol
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Please refer to this study by its identifier: NCT00981071

Sponsors and Collaborators
Armed Forces Capital Hospital, Republic of Korea
Principal Investigator: Jae-Joon Yim, MD Seoul National University Hospital
  More Information

Responsible Party: Sei Won Lee/Division chief of pulmonology, Armed Forces Capital Hospital Identifier: NCT00981071     History of Changes
Other Study ID Numbers: QFTconversion
Study First Received: September 21, 2009
Last Updated: April 7, 2010

Keywords provided by Armed Forces Capital Hospital, Republic of Korea:

Additional relevant MeSH terms:
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections
Antineoplastic Agents
Antiviral Agents
Anti-Infective Agents processed this record on April 28, 2017