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S-100B and Neuron-specific Enolase (NSE) in Spinal Trauma (WBS)

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ClinicalTrials.gov Identifier: NCT00980434
Recruitment Status : Completed
First Posted : September 21, 2009
Last Update Posted : April 4, 2012
Sponsor:
Information provided by:

Study Description
Brief Summary:
The investigators are studying the clinical worth of the serum markers S-100B and NSE in patients with spinal cord injuries e.g. in patients with vertebral fractures. If there is a injury to the neuronal structures these two proteins could be secreted into the serum and add evidence to the severity of the injury.

Condition or disease
Spinal Cord Injury

Study Design

Study Type : Observational
Actual Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Clinical Use of S-100B and NSE in Spinal Cord Injuries
Study Start Date : February 2008
Primary Completion Date : November 2011
Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts

Group/Cohort
1
patients with neurological symptoms
2
patients without neurological symptoms


Outcome Measures

Primary Outcome Measures :
  1. Neurological Symptoms [ Time Frame: 2 weeks ]

Biospecimen Retention:   Samples Without DNA
Serum probe

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   1 Year and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patients from daily practice
Criteria

Inclusion Criteria:

  • vertebral fracture
  • injuries to the vertebral spine

Exclusion Criteria:

  • head trauma
  • polytrauma
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00980434


Locations
Austria
Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
Investigators
Study Chair: Vilmos Vecsei, M.D. Professor Head of Department