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S-100B and Neuron-specific Enolase (NSE) in Spinal Trauma (WBS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00980434
Recruitment Status : Completed
First Posted : September 21, 2009
Last Update Posted : April 4, 2012
Information provided by:
Medical University of Vienna

Brief Summary:
The investigators are studying the clinical worth of the serum markers S-100B and NSE in patients with spinal cord injuries e.g. in patients with vertebral fractures. If there is a injury to the neuronal structures these two proteins could be secreted into the serum and add evidence to the severity of the injury.

Condition or disease
Spinal Cord Injury

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Study Type : Observational
Actual Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Clinical Use of S-100B and NSE in Spinal Cord Injuries
Study Start Date : February 2008
Actual Primary Completion Date : November 2011
Actual Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

patients with neurological symptoms
patients without neurological symptoms

Primary Outcome Measures :
  1. Neurological Symptoms [ Time Frame: 2 weeks ]

Biospecimen Retention:   Samples Without DNA
Serum probe

Information from the National Library of Medicine

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Ages Eligible for Study:   1 Year and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patients from daily practice

Inclusion Criteria:

  • vertebral fracture
  • injuries to the vertebral spine

Exclusion Criteria:

  • head trauma
  • polytrauma

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00980434

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Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
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Study Chair: Vilmos Vecsei, M.D. Professor Head of Department

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Responsible Party: Wolf Harald Dr., Department for Trauma Surgery Identifier: NCT00980434    
Other Study ID Numbers: Wolf-4
First Posted: September 21, 2009    Key Record Dates
Last Update Posted: April 4, 2012
Last Verified: July 2011
Keywords provided by Medical University of Vienna:
vertebral fracture
spinal cord injury
Additional relevant MeSH terms:
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Spinal Cord Injuries
Wounds and Injuries
Spinal Cord Diseases
Central Nervous System Diseases
Nervous System Diseases
Trauma, Nervous System