Genetic Examination of Patients With Primary Multiple Hernia
Recruitment status was: Recruiting
The investigators are performing a genetic study of patients with multiple hernias (at least 3 primary hernias) versus a healthy control group. This genetic information is compared with circulating and subcutaneously biomarkers such as matrix-metalloproteinases (MMP's).
The hypothesis is that patients with multiple hernias have different expression of specific genes compared to the healthy control group.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Genetic Differences Between Patients With Multiple Hernia and a Healthy Control Group|
- Genetic expression of relevant genes between the groups [ Time Frame: 12 months ]
- Amount of serological biomarkers (MMP's) correlated to gene expression [ Time Frame: 12 months ]
|Study Start Date:||June 2009|
|Estimated Study Completion Date:||December 2011|
|Estimated Primary Completion Date:||June 2011 (Final data collection date for primary outcome measure)|
Patients with more than 3 primary hernias
Patients without hernias
Other examinations performed on the patients enrolled in this study:
- Ultrasound (US) examination of the abdominal aorta to discover possible abdominal aortic aneurysms.
- Beightons score to evaluate the degree of joint hypermobility.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00979095
|Herlev Hospital, Herev, Denmark, 2730|
|Contact: Jakob Burcharth, MD 44884488 ext 89434 firstname.lastname@example.org|
|Principal Investigator: Jakob Burcharth, MD|
|Study Director:||Jacob Rosenberg, Prof. MD||Herlev Hospital|
|Principal Investigator:||Jakob Burcharth, MD||Herlev Hospital|