This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Immunohistochemical (IHC) Scoring for Receptors Expression in Breast Tissues

This study has been withdrawn prior to enrollment.
(Personal changes in the company)
Information provided by:
Applied Spectral Imaging Ltd. Identifier:
First received: September 15, 2009
Last updated: January 4, 2016
Last verified: January 2016

The purpose of this study is the identification and classification of human tissues and cytology specimens and elements therein.

Computer aided technology to assist the pathologists to identify, quantify, characterize and report their findings with regards to one or more diagnoses they should perform. In particular and for example: the scoring of the number of elements and their protein (antibody) expression level within a paraffin embedded tissue section.

Breast Cancer

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Concordance Study for Over Expression Level of Antibodies Within Breast Tissues

Resource links provided by NLM:

Further study details as provided by Applied Spectral Imaging Ltd.:

Biospecimen Retention:   Samples Without DNA
Paraffin embedded tissue sections of the breast

Enrollment: 0
Study Start Date: May 2006

Ages Eligible for Study:   20 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
The breast samples were taken from female patients after tru cut biopsies, lumpectomies or mastectomies. Paraffin embedded blocks were prepared from the specimens out of which sections were stained immunohistochemically with the Vision Bio Systems mouse monoclonal antibodies for Estrogen Receptor (NCL-ER-6F11) and Progesterone Receptor (NCL-PGR-312). All stages were performed under the routine procedure of the hospital laboratory.

Inclusion Criteria:

  • Well stained paraffin embedded tissue specimens

Exclusion Criteria:

  • Fade away slides
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Responsible Party: Tsafrir Kolatt, Applied Spectral Imaging Ltd. Identifier: NCT00978276     History of Changes
Other Study ID Numbers: ASI-IHC
Study First Received: September 15, 2009
Last Updated: January 4, 2016

Keywords provided by Applied Spectral Imaging Ltd.:
Over expression of Hormone receptors in carcinoma of the breast sues processed this record on August 22, 2017