Embryo Developmental Capacity After Egg Banking in an Ovum Donation Program
For an efficient "egg banking" system, an equally efficient cryopreservation strategy that ensures the viability of the oocytes is required. Very recently, improved and new methods are yielding satisfactory results. In particular, vitrification is providing excellent results for both survival and clinical outcomes. However, to evaluate the over all out come there are other parameters to be considered. In this sense, capacity development of embryos generated after oocyte vitrification is a major factor when assessing the viability of vitrified oocytes. Accordingly, the evaluation of the capacity of vitrified oocytes to reach the blastocyst stage will be highly valuable to fully assess the effectiveness of the "egg banking" and its contribution to ovum donation programs.
The aim of this study is to evaluate the developmental capacity of vitrified oocytes by their ability to reach the blastocyst stage. The study includes oocyte donation cycles conducted with vitrified versus fresh oocytes.
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
- Mean outcome measures will be survival, fertilization and blastocyst rates and clinical outcome. [ Time Frame: 10 months ]
|Study Start Date:||September 2009|
|Study Completion Date:||May 2014|
|Primary Completion Date:||May 2014 (Final data collection date for primary outcome measure)|
Active Comparator: fresh
Embryo transfer with fresh oocytes
Embryo transfer with vitrified oocytes
|Other: Oocyte Vitrification|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00977821
|Valencia, Spain, 46015|