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Gene - Exercise Research Study (GERS)

This study has been completed.
ClinicalTrials.gov Identifier:
First Posted: September 14, 2009
Last Update Posted: September 14, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
University of Pittsburgh
Information provided by:
University of Maryland
The investigators hypothesize that the degree to which older generally healthy but sedentary men and women improve a number of cardiovascular (CV) disease risk factors with 6 months of highly-standardized endurance exercise training will be a function of common genetic variations in candidate genes.

Condition Intervention
Cardiovascular Disease Risk Factors Behavioral: Endurance exercise training

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Primary Purpose: Prevention
Official Title: Impact of Common Genetic Polymorphisms on CV Disease Risk Factor Changes With Endurance Exercise Training

Resource links provided by NLM:

Further study details as provided by University of Maryland:

Primary Outcome Measures:
  • Cardiovascular Disease Risk Factors [ Time Frame: ~9 months ]

Enrollment: 225
Study Start Date: June 1998
Primary Completion Date: December 2004 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Endurance Exercise Training Behavioral: Endurance exercise training


Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • generally healthy
  • free from CV disease
  • ability to undergo exercise training

Exclusion Criteria:

  • previous history of CV disease
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00976742

United States, Maryland
University of Maryland Dept of Kinesiology
College Park, Maryland, United States, 20742-2611
Sponsors and Collaborators
University of Maryland
University of Pittsburgh
  More Information

Responsible Party: James Hagberg, PhD, Professor, Principal Investigator, University of Maryland College Park
ClinicalTrials.gov Identifier: NCT00976742     History of Changes
Other Study ID Numbers: AG17474
First Submitted: September 11, 2009
First Posted: September 14, 2009
Last Update Posted: September 14, 2009
Last Verified: September 2009

Keywords provided by University of Maryland:
plasma lipoprotein lipids
body composition
glucose tolerance
inflammation markers
insulin sensitivity
coagulation markers

Additional relevant MeSH terms:
Cardiovascular Diseases