Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study (FATS)
|ClinicalTrials.gov Identifier: NCT00976014|
Recruitment Status : Unknown
Verified September 2009 by University of Washington.
Recruitment status was: Enrolling by invitation
First Posted : September 14, 2009
Last Update Posted : September 22, 2009
This observational study looks at Carotid Stenosis in two groups of subjects using a non-invasive procedure, B-mode ultrasound.
One group of subjects has had long-term intensive lipid altering therapy (lowering LDL-C plus raising HDL-C). The second group of patients has been on conventional "standard of care" treatment for carotid stenosis.
The study will look at the Carotid Intima-media Thickness (CMIT) in both groups.
Hypothesis: CIMT will differ between the two groups, such that the CIMT will be less in the subjects on intensive lipid altering therapy.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||55 participants|
|Observational Model:||Case Control|
|Official Title:||Effects of Long-term Therapy With LDL-lowering Plus HDL Raising on Carotid Intima-media Thickness (CIMT) - Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study|
|Study Start Date :||September 2006|
|Estimated Primary Completion Date :||September 2011|
|Estimated Study Completion Date :||September 2011|
Intensive Lipid-lowering therapy
Subjects on intensive long-term lipid lowering therapy (lowering LDL-C plus raising of HDL-C).
Subjects with Atherosclerosis who have been on conventional "standard of care" treatment.
- Carotid Intima-media Thickness [ Time Frame: Up to 3 years ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00976014
|United States, Washington|
|University of Washington|
|Seattle, Washington, United States, 98105|
|Principal Investigator:||Xue-Qiao Zhao||University of Washington|