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Psychophysiological Correlates of Mindfulness Based Cognitive Therapy (MBCT) in Recurrent Depression (MBCT & EEG)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00974077
First Posted: September 10, 2009
Last Update Posted: December 23, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Prof. Dr. Martin Hautzinger, University Hospital Tuebingen
  Purpose
The study investigates cognitive attention, rumination and psychophysiological (EEG) processes in healthy subjects and remitted patients with at least three previous depressive episodes. The investigators expect that Mindfulness Based Cognitive Therapy prevents future depressive episodes and has influence on cognitive and psychophysiological measures.

Condition Intervention
Depression Behavioral: Mindfulness Based Cognitive Therapy Other: Waiting List Control

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Psychophysiological Correlates of Mindfulness and Attention in Recurrent Depression and Healthy Volunteers

Further study details as provided by Prof. Dr. Martin Hautzinger, University Hospital Tuebingen:

Primary Outcome Measures:
  • Relapse (MDE) [ Time Frame: 12 month ]

Secondary Outcome Measures:
  • Electroencephalography (EEG) [ Time Frame: 6 month ]

Enrollment: 120
Study Start Date: September 2008
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Wait List Control
Patients do ot receive psychotherapy. The wait list control group will be assessed according to study protocol and offered MBCT after 6 month
Other: Waiting List Control
Patients receive MBCT with a delay of 6 months.
Experimental: Mindfulness Based Cognitive Therapy
The published protocol of MBCT will be used. This is an eight week group program. Participants learn mindfulness techniques but also cognitive techniques to prevent new depressive episodes
Behavioral: Mindfulness Based Cognitive Therapy
Group treatment over 8 weeks with training in meditation, stress regulation, shift attention, stay present, in addition with cognitive and behavioral strategies (following Williams et al. Manual 2002)

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • recurrent depression with at least 3 previous MD-episodes, currently remitted (no symptoms)

Exclusion Criteria:

  • current depression
  • lifetime schizophrenia
  • bipolar or schizoaffective disorder
  • any neurological disorders
  • other psychopathology during last 3 years
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00974077


Locations
Germany
Department of Psychology University of Tuebingen
Tuebingen, Germany, D-72072
Sponsors and Collaborators
University Hospital Tuebingen
Investigators
Principal Investigator: Martin Hautzinger, PhD Eberhard Karls University
  More Information

Publications:
Responsible Party: Prof. Dr. Martin Hautzinger, University Professor of Clinical Psychology and Psychotherapy, University Hospital Tuebingen
ClinicalTrials.gov Identifier: NCT00974077     History of Changes
Other Study ID Numbers: HA1399/16-1
First Submitted: September 9, 2009
First Posted: September 10, 2009
Last Update Posted: December 23, 2014
Last Verified: December 2014

Keywords provided by Prof. Dr. Martin Hautzinger, University Hospital Tuebingen:
recurrent depression,
mindfulness training
attention
Evoked EEG potentials
Relapse prevention in recurrent depression

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders