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Psychophysiological Correlates of Mindfulness Based Cognitive Therapy (MBCT) in Recurrent Depression (MBCT & EEG)

This study has been completed.
Information provided by (Responsible Party):
Prof. Dr. Martin Hautzinger, University Hospital Tuebingen Identifier:
First received: September 9, 2009
Last updated: December 19, 2014
Last verified: December 2014
The study investigates cognitive attention, rumination and psychophysiological (EEG) processes in healthy subjects and remitted patients with at least three previous depressive episodes. The investigators expect that Mindfulness Based Cognitive Therapy prevents future depressive episodes and has influence on cognitive and psychophysiological measures.

Condition Intervention
Depression Behavioral: Mindfulness Based Cognitive Therapy Other: Waiting List Control

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Psychophysiological Correlates of Mindfulness and Attention in Recurrent Depression and Healthy Volunteers

Further study details as provided by Prof. Dr. Martin Hautzinger, University Hospital Tuebingen:

Primary Outcome Measures:
  • Relapse (MDE) [ Time Frame: 12 month ]

Secondary Outcome Measures:
  • Electroencephalography (EEG) [ Time Frame: 6 month ]

Enrollment: 120
Study Start Date: September 2008
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Wait List Control
Patients do ot receive psychotherapy. The wait list control group will be assessed according to study protocol and offered MBCT after 6 month
Other: Waiting List Control
Patients receive MBCT with a delay of 6 months.
Experimental: Mindfulness Based Cognitive Therapy
The published protocol of MBCT will be used. This is an eight week group program. Participants learn mindfulness techniques but also cognitive techniques to prevent new depressive episodes
Behavioral: Mindfulness Based Cognitive Therapy
Group treatment over 8 weeks with training in meditation, stress regulation, shift attention, stay present, in addition with cognitive and behavioral strategies (following Williams et al. Manual 2002)


Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • recurrent depression with at least 3 previous MD-episodes, currently remitted (no symptoms)

Exclusion Criteria:

  • current depression
  • lifetime schizophrenia
  • bipolar or schizoaffective disorder
  • any neurological disorders
  • other psychopathology during last 3 years
  Contacts and Locations
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Please refer to this study by its identifier: NCT00974077

Department of Psychology University of Tuebingen
Tuebingen, Germany, D-72072
Sponsors and Collaborators
University Hospital Tuebingen
Principal Investigator: Martin Hautzinger, PhD Eberhard Karls University
  More Information

Responsible Party: Prof. Dr. Martin Hautzinger, University Professor of Clinical Psychology and Psychotherapy, University Hospital Tuebingen Identifier: NCT00974077     History of Changes
Other Study ID Numbers: HA1399/16-1
Study First Received: September 9, 2009
Last Updated: December 19, 2014

Keywords provided by Prof. Dr. Martin Hautzinger, University Hospital Tuebingen:
recurrent depression,
mindfulness training
Evoked EEG potentials
Relapse prevention in recurrent depression

Additional relevant MeSH terms:
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders processed this record on September 21, 2017