Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00969670|
Recruitment Status : Unknown
Verified November 2009 by Tel-Aviv Sourasky Medical Center.
Recruitment status was: Recruiting
First Posted : September 1, 2009
Last Update Posted : November 25, 2009
Samples of sputum from asthmatic children, between 5-17 years, will be collected during two years of the study period to perform tests Particle Size Distribution (PSD) and Shape Analysis (SA) of the particulate matter in the sputum and a biochemical reaction to evaluate the activity of Heme Oxygenase-1 protein in sputum cell supernatants.
Each child will perform Pulmonary Function Testing (PFT) and Induced Sputum (IS) as a routine part of diagnosis of asthma.
Parents will be asked to complete a questionnaire including questions on their child's respiratory symptoms in the last 12 months as well as socioeconomic factors. Parents will be asked to give informed written consent for their child's participation in the study.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Observational Model:||Ecologic or Community|
|Official Title:||Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.|
|Study Start Date :||October 2009|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00969670
|Pulmonary Laboratory of Tel Aviv Sourasky Medical Center||Recruiting|
|Tel Aviv, Israel|
|Contact: Elizabeth Fierman, PhD email@example.com|
|Contact: Daria Bliznuk, BcS firstname.lastname@example.org|
|Principal Investigator: Elizabeth Fierman, PhD|