The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva
Recruitment status was: Recruiting
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva|
|Study Start Date:||July 2009|
|Estimated Primary Completion Date:||December 2010 (Final data collection date for primary outcome measure)|
Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection.
Free radicals can be defined as molecules or molecular fragments with an unpaired electron which imparts certain characteristics to the free radicals such as reactivity . Reactive free radicals are able to produce chemical modifications and to damage proteins, lipids, carbohydrates and nucleotides in the tissues.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00969241
|department of oral and maxillofacial surgery, Baruch Padeh Medical Center|
|Tieberia, Israel, Poria, Israel|
|Principal Investigator:||eran front, Dr.||department of oral and maxillofacial surgery|