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Coronary Artery Stent Evaluation With 320-slice Computed Tomography - The CArS 320 Study (CARS-320)

This study has been completed.
Information provided by (Responsible Party):
Marc Dewey, Charite University, Berlin, Germany Identifier:
First received: August 27, 2009
Last updated: July 22, 2014
Last verified: July 2014
The investigators aim at analyzing the diagnostic accuracy of 320-row CT for coronary stents.

Coronary Artery Stenosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Coronary Artery Stent Evaluation With 320-slice Computed Tomography - The CArS 320 Study

Further study details as provided by Charite University, Berlin, Germany:

Estimated Enrollment: 90
Study Start Date: April 2009
Primary Completion Date: November 2011 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   40 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients who underwent coronary artery stent placement in the past and are clinically indicated to undergo conventional coronary angiography.

Inclusion Criteria:

  • Suspected coronary artery in-stent restenoses based on clinical findings or findings on other noninvasive imaging tests and planned coronary angiography within the next 14 days.
  • Able to understand and willing to sign the Informed CF.

Exclusion Criteria:

  • Creatinine of above 2.0 mg/dl
  • Age below 40 years
  • Women of child bearing potential (no hysterectomy, no menopause, or menopause since less than 12 months) must demonstrate a negative pregnancy test performed within 24 hours before CT.
  • Resting heart rate above 70 beats per minute and contraindications to beta blockers (e.g. moderate to severe bronchospastic disease, asthma)
  • Atrial fibrillation, uncontrolled tachycardia, A-V block II or III degree or other non-sinus rhythms
  • Inability to hold the breath for 10 seconds
  • Hypotension < 80 mmHg systolic
  • Unstable angina pectoris, acute myocardial infarction < 48h
  • Continuous therapy with Dipyridamol
  • Severe aortic stenosis
  Contacts and Locations
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Please refer to this study by its identifier: NCT00967876

Berlin, Germany, 10117
Sponsors and Collaborators
Charite University, Berlin, Germany
Principal Investigator: Marc Dewey, MD, PhD Charité
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Marc Dewey, PD, Charite University, Berlin, Germany Identifier: NCT00967876     History of Changes
Other Study ID Numbers: EA1/133/08
Study First Received: August 27, 2009
Last Updated: July 22, 2014

Keywords provided by Charite University, Berlin, Germany:
Men or women of any ethnic group scheduled to undergo conventional coronary angiography for suspected coronary artery stent stenosis

Additional relevant MeSH terms:
Coronary Stenosis
Coronary Disease
Myocardial Ischemia
Heart Diseases
Cardiovascular Diseases
Vascular Diseases processed this record on April 26, 2017