Study of Tissue Samples From Patients With Glioma or Other Brain Tumors

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2009 by National Cancer Institute (NCI).
Recruitment status was  Recruiting
Information provided by:
National Cancer Institute (NCI) Identifier:
First received: August 26, 2009
Last updated: April 20, 2010
Last verified: August 2009

RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.

PURPOSE: This research study is looking at tissue samples from patients with glioma or other brain tumors.

Condition Intervention
Brain and Central Nervous System Tumors
Other: laboratory biomarker analysis
Other: pharmacogenomic studies

Study Type: Observational
Official Title: Identification of Genes Involved in the Pathogenesis of Gliomas by Transcriptome Analysis

Resource links provided by NLM:

Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:
  • Pathophysiology of gliomas and identification of molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches [ Designated as safety issue: No ]

Estimated Enrollment: 150
Study Start Date: November 2003
Estimated Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Detailed Description:



  • To better understand the pathophysiology of gliomas and identify molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches.


  • To compare gene expression profiles, in terms of response to treatment, and attempt to isolate subgroups of patients with objective response to certain types of chemotherapy or radiotherapy.

OUTLINE: This is a multicenter study.

Biological samples are collected from patients at time of surgery for diagnostic and/or treatment purposes.


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No


  • Histologically confirmed glioma of any grade or rare primary brain tumor

    • Planning surgery to remove the tumor


  • No urgent situation
  • No known or suspected active infection
  • Must not be deprived of liberty or protected by law
  • Not pregnant or nursing


  • No concurrent participation in other trials that require a period of exclusion
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00967200

CHU Montpellier Recruiting
Montpellier, France, 34295
Contact: Luc Bauchet, MD    Not Available      
Clinique Gui de Chauliac Recruiting
Montpellier, France, 34295
Contact: Luc Bauchet, MD    33-67-542-494      
Sponsors and Collaborators
University Hospital, Montpellier
Investigator: Luc Bauchet, MD University Hospital, Montpellier
  More Information

No publications provided Identifier: NCT00967200     History of Changes
Other Study ID Numbers: CDR0000626732, CHUM-DGS-2003/0402, CHUM-UF7745, INCA-RECF0467
Study First Received: August 26, 2009
Last Updated: April 20, 2010
Health Authority: Unspecified

Keywords provided by National Cancer Institute (NCI):
adult grade I meningioma
adult grade II meningioma
adult anaplastic meningioma
adult papillary meningioma
adult anaplastic astrocytoma
adult diffuse astrocytoma
adult glioblastoma
adult giant cell glioblastoma
adult gliosarcoma
adult pilocytic astrocytoma
adult pineal gland astrocytoma
adult subependymal giant cell astrocytoma
adult brain stem glioma
adult choroid plexus tumor
adult craniopharyngioma
adult ependymoblastoma
adult medulloblastoma
adult supratentorial primitive neuroectodermal tumor (PNET)
adult anaplastic ependymoma
adult ependymoma
adult myxopapillary ependymoma
adult subependymoma
meningeal melanocytoma
adult meningeal hemangiopericytoma
adult anaplastic oligodendroglioma
adult oligodendroglioma
adult pineoblastoma
adult pineocytoma
adult mixed glioma
recurrent adult brain tumor

Additional relevant MeSH terms:
Central Nervous System Neoplasms
Nervous System Neoplasms
Neoplasms by Site
Nervous System Diseases processed this record on October 13, 2015