Computed Tomography (CT) and Lung Function Data Collection for Computational Fluid Dynamics (CFD) in Chronic Obstructive Pulmonary Disease (COPD) Patients
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|ClinicalTrials.gov Identifier: NCT00966459|
Recruitment Status : Completed
First Posted : August 27, 2009
Last Update Posted : September 1, 2009
In this study, 20 COPD patients will undergo a high-resolution/multi slice CT scan and lung function tests to obtain patient specific geometries of the central and peripheral small airways and patient specific boundary conditions.
With Computational Fluid Dynamics (CFD), the investigators will be able to reconstruct the geometry and measure the resistance of the peripheral airways.
In a later stage, CFD will be used to simulate the reaction of the airways on various inhalation medications.
|Condition or disease||Intervention/treatment||Phase|
|Chronic Obstructive Pulmonary Disease||Procedure: Computed Tomography||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Computed Tomography (CT) and Lung Function Data Collection for Computational Fluid Dynamics (CFD) in COPD Patients|
|Study Start Date :||November 2008|
|Actual Primary Completion Date :||April 2009|
|Actual Study Completion Date :||May 2009|
Procedure: Computed Tomography
1 low-dose CT is taken
- To obtain patient specific geometries of the central and peripheral small airways
- To obtain patient specific boundary conditions
- To measure the resistance of the peripheral airways
- To measure the reaction of the airways on various inhalation medications
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00966459
|University Hospital Antwerp|
|Edegem, Antwerp, Belgium, 2650|